Kinase profiling results of kinases in KIF 2C6TA_DT5 (CDK2, PDB code: 2C6T, chain A)
Template Kinase: CDK2
Template inhibitor: 2c6m

 8 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK4CMGC
ABL1TK
FGFR1TK
FGFR2TK
METTK
SRCTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK4CMGC 
ABL1TK 
FGFR1TK 
FGFR2TK 
METTK 
SRCTK