Kinase profiling results of kinases in KIF 2EXMA_ZIP (CDK2, PDB code: 2EXM, chain A)
Template Kinase: CDK2
Template inhibitor: MLS000079197

 12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ROCK2AGC 
PRKACAAGC 
CHEK1CAMK 
PIM1CAMK 
CDK2CMGC 
GSK3BCMGC 
MAPK8CMGC 
AURKBOther 
TTKOther 
JAK2TK 
JAK3TK 
LCKTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PRKACAAGC
ROCK2AGC
CHEK1CAMK
PIM1CAMK
CDK2CMGC
GSK3BCMGC
MAPK8CMGC
AURKBOther
TTKOther
JAK2TK
JAK3TK
LCKTK