Kinase profiling results of kinases in KIF 2IW9A_4SP (CDK2, PDB code: 2IW9, chain A)
Template Kinase: CDK2
Template inhibitor: nu6102

 30 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ROCK2AGC
RPS6KA2AGC
RPS6KA2CAMK
RPS6KA3AGC
RPS6KA6AGC
RPS6KA6CAMK
NUAK1CAMK
NUAK2CAMK
TSSK1BCAMK
CDK2CMGC
CDK4CMGC
CLK2CMGC
CLK4CMGC
AURKAOther
AURKBOther
AURKCOther
EIF2AK2Other
TTKOther
TNK2TK
FERTK
JAK2TK
JAK3TK
YES1TK
LCKTK
PTK6TK
BMXTK
NTRK3TK
MAP3K10TKL
MAP3K11TKL
MAP3K9TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
ROCK2AGC 
RPS6KA2AGC 
RPS6KA3AGC 
RPS6KA6AGC 
NUAK1CAMK 
NUAK2CAMK 
TSSK1BCAMK 
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK4CMGC 
CDK6CMGC 
CDK6CMGC 
CLK2CMGC 
CLK4CMGC 
AURKAOther 
AURKBOther 
AURKCOther 
TTKOther 
BMXTK 
FERTK 
JAK2TK 
JAK3TK 
LCKTK 
NTRK3TK 
PTK6TK 
TNK2TK 
YES1TK 
MAP3K10TKL 
MAP3K11TKL 
MAP3K9TKL