Kinase profiling results of kinases in KIF 2VTOA_LZ8 (CDK2, PDB code: 2VTO, chain A)
Template Kinase: CDK2
Template inhibitor: pyrazole diamide, 22

10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
GSK3BCMGC 
MAPK1CMGC 
MAPK14CMGC 
AURKAOther 
MAP2K1STE 
ABL1TK 
EPHB3TK 
SRCTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
CDC2CMGC  
CDC2CMGC  
CDK2CMGC  
GSK3BCMGC  
MAPK1CMGC  
MAPK14CMGC  
AURKAOther  
MAP2K1STE  
ABL1TK  
EPHB3TK  
SRCTK