Kinase profiling results of kinases in KIF 3MIAA_ANP (CDK9, PDB code: 3MIA, chain A)
Template Kinase: CDK9
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 18 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
RPS6KA1AGC
RPS6KA1CAMK
CASKCAMK
DAPK1CAMK
CHEK2CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
EIF2AK2Other
STK24STE
MAP2K1STE
SRCTK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT2AGC
RPS6KA1AGC
CHEK2CAMK
DAPK1CAMK
CDK2CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
MAP2K1STE
STK24STE
SRCTK
IRAK4TKL