Kinase profiling results of kinases in KIF 3NR9A_NR9 (CLK2, PDB code: 3NR9, chain A)
Template Kinase: CLK2
Template inhibitor: Cdk1 Inhibitor IV, RO-3306

 6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK9CMGC
CLK2CMGC
GSK3ACMGC
MAPK1CMGC

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
CDC2CMGC 
CDC2CMGC 
CDK2CMGC 
CDK9CMGC 
CLK2CMGC 
GSK3ACMGC 
MAPK1CMGC