Kinase profiling results of kinases in KIF 2J90A_IZA (DAPK3, PDB code: 2J90, chain A)
Template Kinase: DAPK3
Template inhibitor: Pyridone 6

40 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
PRKCDAGC
PKN1AGC
RPS6KA4AGC
RPS6KA4CAMK
RPS6KA1AGC
RPS6KA1CAMK
RPS6KA2AGC
RPS6KA2CAMK
RPS6KA3AGC
RPS6KA6AGC
RPS6KA6CAMK
BRSK1CAMK
BRSK2CAMK
CHEK1CAMK
MARK2CAMK
MARK4CAMK
NUAK1CAMK
DAPK1CAMK
DAPK2CAMK
DAPK3CAMK
STK17ACAMK
PHKG1CAMK
PIM1CAMK
PIM3CAMK
PRKD1CAMK
PRKD2CAMK
PRKD3CAMK
CHEK2CAMK
TSSK1BCAMK
CDK2CMGC
NLKCMGC
MAPK14CMGC
AURKAOther
AURKBOther
AURKCOther
TBK1Other
NEK1Other
PLK1Other
PLK3Other
HCKTK
BRAFTKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
GRK6AGC    
PDPK1AGC    
PKN1AGC    
PRKCAAGC    
PRKCDAGC    
RPS6KA1AGC    
RPS6KA2AGC    
RPS6KA3AGC    
RPS6KA4AGC    
RPS6KA6AGC    
BRSK1CAMK    
BRSK2CAMK    
CHEK1CAMK    
CHEK2CAMK    
DAPK1CAMK    
DAPK2CAMK    
DAPK3CAMK    
MARK2CAMK    
MARK4CAMK    
NUAK1CAMK    
PHKG1CAMK    
PIM1CAMK    
PIM3CAMK    
PRKD1CAMK    
PRKD2CAMK    
PRKD3CAMK    
STK17ACAMK    
TSSK1BCAMK    
CDK2CMGC    
MAPK14CMGC    
NLKCMGC    
AURKAOther    
AURKBOther    
AURKCOther    
NEK1Other    
PLK1Other    
PLK3Other    
TBK1Other    
HCKTK    
BRAFTKL