Kinase profiling results of kinases in KIF 1Q3WA_ATU (GSK3B, PDB code: 1Q3W, chain A)
Template Kinase: GSK3B
Template inhibitor: alsterpaullone

 24 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
RPS6KA2AGC
RPS6KA2CAMK
RPS6KA3AGC
RPS6KA6AGC
RPS6KA6CAMK
BRSK1CAMK
BRSK2CAMK
CHEK1CAMK
NUAK1CAMK
SIK2CAMK
PHKG1CAMK
PIM3CAMK
CHEK2CAMK
CDK2CMGC
CDK3CMGC
CDK5CMGC
CDK9CMGC
DYRK2CMGC
GSK3ACMGC
GSK3BCMGC
AURKAOther
PAK1STE
PAK2STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PDPK1AGC    
RPS6KA2AGC    
RPS6KA3AGC    
RPS6KA6AGC    
BRSK1CAMK    
BRSK2CAMK    
CHEK1CAMK    
CHEK2CAMK    
NUAK1CAMK    
PHKG1CAMK    
PIM3CAMK    
SIK2CAMK    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
CDK3CMGC    
CDK5CMGC    
CDK6CMGC    
CDK6CMGC    
CDK9CMGC    
DYRK2CMGC    
GSK3ACMGC    
GSK3BCMGC    
AURKAOther    
PAK1STE    
PAK2STE