Kinase profiling results of kinases in KIF 3F88A_3HT (GSK3B, PDB code: 3F88, chain A)
Template Kinase: GSK3B
Template inhibitor: SMR000144908

 4 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PRKCQAGC
GSK3BCMGC
MAP3K1STE

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
PRKCQAGC 
CDC2CMGC 
CDC2CMGC 
GSK3BCMGC