Kinase profiling results of kinases in KIF 1JQHA_ANP (IGF1R, PDB code: 1JQH, chain A)
Template Kinase: IGF1R
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

 21 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
RPS6KA1AGC
RPS6KA1CAMK
OXSR1STE
STK24STE
ABL1TK
ALKTK
MERTKTK
EGFRTK
ERBB3TK
EPHA3TK
PTK2TK
PTK2BTK
FGFR1TK
FGFR2TK
IGF1RTK
INSRTK
MST1RTK
RETTK
SRCTK
HCKTK
LCKTK
ZAP70TK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
RPS6KA1AGC
OXSR1STE
STK24STE
ABL1TK
ALKTK
EGFRTK
EPHA3TK
FGFR1TK
FGFR2TK
HCKTK
IGF1RTK
INSRTK
LCKTK
MERTKTK
MST1RTK
PTK2TK
PTK2BTK
RETTK
SRCTK
ZAP70TK