Kinase profiling results of kinases in KIF 3NW7A_LGV (IGF1R, PDB code: 3NW7, chain A)
Template Kinase: IGF1R
Template inhibitor: AMG_706

 3 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
IGF1RTK  
JAK2TK  
TEKTK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C
IGF1RTK 
JAK2TK 
TEKTK