Kinase profiling results of kinases in KIF 3QQUA_01P (IGF1R, PDB code: 3QQU, chain A)
Template Kinase: IGF1R
Template inhibitor: N~2~-[3-Methoxy-4-(Morpholin-4-Yl)phenyl]-N~4~-(Quinolin-3-Yl)pyrimidine-2,4-Diamine

21 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
RPS6KA1AGC  
RPS6KA1CAMK  
ABL1TK  
ALKTK  
CSKTK  
EGFRTK  
EPHB4TK  
PTK2TK  
FGFR1TK  
FGFR2TK  
IGF1RTK  
INSRTK  
JAK2TK  
RETTK  
SRCTK  
YES1TK  
BLKTK  
LCKTK  
ZAP70TK  
TEKTK  
KDRTK  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C
RPS6KA1AGC       
CDC2CMGC       
CDC2CMGC       
ABL1TK       
ALKTK       
BLKTK       
CSKTK       
EGFRTK       
EPHB4TK       
FGFR1TK       
FGFR2TK       
IGF1RTK       
INSRTK       
JAK2TK       
KDRTK       
LCKTK       
PTK2TK       
RETTK       
SRCTK       
TEKTK       
YES1TK       
ZAP70TK