Kinase profiling results of kinases in KIF 3EQGA_ADP (MAP2K1, PDB code: 3EQG, chain A)
Template Kinase: MAP2K1
Template inhibitor: Adenosine-5'-diphosphate

 12 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CDK2CMGC
CDK9CMGC
GSK3BCMGC
STK24STE
MAP2K1STE
MAP2K2STE
MAP2K4STE
ABL1TK
RETTK
ZAP70TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
GRK6AGC
CDK2CMGC
CDK9CMGC
GSK3BCMGC
MAP2K1STE
MAP2K2STE
STK24STE
ABL1TK
RETTK
ZAP70TK
IRAK4TKL