Kinase profiling results of kinases in KIF 2B1PA_AIZ (MAPK10, PDB code: 2B1P, chain A)
Template Kinase: MAPK10
Template inhibitor: AIZ

7 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C C C C C C C C
MAPK10CMGC          
MAPK8CMGC          
MAPK9CMGC          
MAPK14CMGC          
AURKAOther          
AURKBOther          

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C C C C C C C
CDC2CMGC          
CDC2CMGC          
MAPK10CMGC          
MAPK14CMGC          
MAPK8CMGC          
MAPK9CMGC          
AURKAOther          
AURKBOther