Kinase profiling results of kinases in KIF 3FV8A_JK3 (MAPK10, PDB code: 3FV8, chain A)
Template Kinase: MAPK10
Template inhibitor: piperazine amide, 4g

 3 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
MAPK10CMGC 
MAPK8CMGC 
MAPK14CMGC 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C
MAPK10CMGC  
MAPK14CMGC  
MAPK8CMGC