Kinase profiling results of kinases in KIF 2W5AA_ADP (NEK2, PDB code: 2W5A, chain A)
Template Kinase: NEK2
Template inhibitor: Adenosine-5'-diphosphate

 6 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
CHEK2CAMK
CDK2CMGC
NEK2Other
PLK1Other
TTKOther
PTK2BTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CHEK2CAMK
CDK2CMGC
NEK2Other
PLK1Other
TTKOther
PTK2BTK