Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
18 AKT1 related diseases 
H00539PTEN hamartoma tumor syndrome (PHTS)
hsa05142Chagas disease (American trypanosomiasis)
hsa05145Toxoplasmosis
hsa05152Tuberculosis
hsa05160Hepatitis C
hsa05162Measles
hsa05164Influenza A
hsa05169Epstein-Barr virus infection
hsa05215Prostate cancer
hsa05218Melanoma
hsa05220Chronic myeloid leukemia
hsa05221Acute myeloid leukemia
hsa05222Small cell lung cancer
114480Breast cancer, somatic
114500Colorectal cancer, somatic
167000Ovarian cancer, somatic
176920Proteus syndrome, somatic
181500{Schizophrenia, susceptibility to}
Summary of query kinase
Query kinase AKT1 (P31749)
Kinase group AGC
Number of conformation types 2 
Number of structural templates 10 (Total 955 inhibitors)
Number of AKT1 related diseases 18 (H00539 hsa05142 hsa05145 hsa05152 hsa05160 hsa05162 hsa05164 hsa05169 ...
Number of allelic variants 1 (E17K
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
B 9 3OCBA_XM1
(AKT1)
AGC XM1 I 10 99 23
F 1 3O96A_IQO
(AKT1)
AGC 1,3-Dihydro-... III 1 98 17