Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
9 KIT related diseases 
H00003Acute myeloid leukemia (AML)
H00170Piebaldism
hsa05221Acute myeloid leukemia
606764Gastrointestinal stromal tumor, somatic
273300Germ cell tumors
601626Leukemia, acute myeloid
OMIM
(164920)
Mast cell leukemia
OMIM
(164920)
Mastocytosis with associated hematologic disorder
OMIM
(164920)
Piebaldism
Summary of query kinase
Query kinase PDGFRA (P16234), reference kinase: KIT (P10721)
Kinase group TK
Number of conformation types 2 
Number of structural templates 4 (Total 585 inhibitors)
Number of KIT related diseases 9 (H00003 H00170 hsa05221 606764 273300 601626 OMIM:164920 OMIM:164920 ...
Number of allelic variants 15 (D816H D816V D816Y D820G E583K E839K F584C F584L G664R K642E ...
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A 1 1PKGA_ADP
(KIT)
TK Adenosine-5'... I 10 10 42
E 3 3G0EA_B49
(KIT)
TK Sunitinib I 37 40 78