Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
6 CHEK2 related diseases 
H00881Li-Fraumeni syndrome
OMIM
(604373)		{Breast and colorectal cancer, susceptibility to}
114480{Breast cancer, susceptibility to}
609265Li-Fraumeni syndrome
259500Osteosarcoma, somatic
176807{Prostate cancer, familial, susceptibility to}
Summary of query kinase
Query kinase PRKD1 (Q15139), reference kinase: CHEK2 (O96017)
Kinase group CAMK
Number of conformation types 2 
Number of structural templates 12 (Total 276 inhibitors)
Number of CHEK2 related diseases 6 (H00881 OMIM:604373 114480 609265 259500 176807) 
Number of allelic variants 10 (A17S E239K E239X I157T P85L R145W R180H R181C R181H S428F) 
Select
Template		 Comformation
Type 		 No. of
Templates		 Representative
Template		 Kinase
Group		 Representative
Inhibitor		 Inhibitor
Type		 No. of
Kinases		 No. of
Inhibitors		 No. of
Diseases
A 4 2XM8A_B4W
(CHEK2)		 CAMK PI_103 I 12 54 18
B 8 2CN5A_ADP
(CHEK2)		 CAMK Adenosine-5'... I 16 6 30