Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
4 JAK3 related diseases 
H00091T-B+Severe combined immunodeficiencies (SCIDs)
hsa05162Measles
hsa05169Epstein-Barr virus infection
600802SCID, autosomal recessive, T-negative/B-positive type
Summary of query kinase
Query kinase JAK3 (P52333)
Kinase group TK
Number of conformation types 2 
Number of structural templates 4 (Total 450 inhibitors)
Number of JAK3 related diseases 4 (H00091 hsa05162 hsa05169 600802
Number of allelic variants 5 (A58X C565X D169E R445X Y100C
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A 3 1YVJA_4ST
(JAK3)
TK staurosporine I 96 90 126
B 1 3LXKA_MI1
(JAK3)
TK CP690550 I 5 23 27