Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
9 MET related diseases 
H00018Gastric cancer
H00021Renal cell carcinoma
H00046Cholangiocarcinoma
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa05144Malaria
hsa05218Melanoma
611015{Autism suseptibility 9}
114550Hepatocellular carcinoma, childhood type
605074Renal cell carcinoma, papillary, familial and somatic
Summary of query kinase
Query kinase MET (P08581)
Kinase group TK
Number of conformation types 4 
Number of structural templates 26 (Total 904 inhibitors)
Number of MET related diseases 9 (H00018 H00021 H00046 hsa05120 hsa05144 hsa05218 611015 114550 ...
Number of allelic variants 10 (D1246N H1112R K1262R L1213V M1149T M1268I T1191I V1206L V1238I Y1248C
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A 3 2RFNA_AM7
(MET)
TK pyrimidone, 22 I 10 41 22
B 3 2WKMA_PFY
(MET)
TK PHA-665752 I 38 34 98
D 12 1R0PA_KSA
(MET)
TK k-252a I 28 79 64
E 8 3LQ8A_88Z
(MET)
TK AZD_1152HQPA II 19 71 36