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Example2
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
1 PRKAA1 related diseases
hsa05410
Hypertrophic cardiomyopathy (HCM)
Summary of query kinase
Query kinase
PRKAA1 (
Q13131
)
Kinase group
CAMK
Number of conformation types
0
Number of structural templates
9 (
Total 46 inhibitors
)
Number of PRKAA1 related diseases
1 (
hsa05410
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
4
2HZ4A_4ST
(ABL1)
CAMK
staurosporine
I
159
103
156
A
2HZ4A_4ST
(ABL1)
CAMK
staurosporine
I
159
103
156
159
103
156
A
2F4JA_VX6
(ABL1)
CAMK
VX-680
I
110
109
134
110
109
134
A
2XYNA_VX6
(ABL2)
CAMK
VX-680
I
79
101
105
79
101
105
A
1AGWA_SU2
(FGFR1)
CAMK
SU 4984
I
77
81
111
77
81
111
B
5
1OKYA_STU
(PDPK1)
CAMK
staurosporine
I
179
67
109
B
1OKYA_STU
(PDPK1)
CAMK
staurosporine
I
179
67
109
179
67
109
B
1OKZA_UCN
(PDPK1)
CAMK
UCN 02
I
179
60
109
179
60
109
B
2PE2A_464
(PDPK1)
CAMK
Indolinone b...
I
134
156
104
134
156
104
B
3EFWA_AK8
(AURKA)
CAMK
3efw
I
100
59
105
100
59
105
B
2BMCA_MPY
(AURKA)
CAMK
PHA-680632
I
107
108
107
107
108
107