Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
11 RET related diseases 
H00032Thyroid cancer
H00822Renal agenesis and Renal adysplasia
H00910Hirschsprung disease (HD)
H00916Congenital central hypoventilation syndrome (CCHS)
209880Central hypoventilation syndrome, congenital
142623{Hirschsprung disease, susceptibility to, 1}
155240Medullary thyroid carcinoma
171400Multiple endocrine neoplasia IIA
162300Multiple endocrine neoplasia IIB
171300Pheochromocytoma
191830Renal agenesis
Summary of query kinase
Query kinase RET (P07949)
Kinase group TK
Number of conformation types 2 
Number of structural templates 7 (Total 285 inhibitors)
Number of RET related diseases 11 (H00032 H00822 H00910 H00916 209880 142623 155240 171400 ...
Number of allelic variants 50 (A45A A640G C380R C609R C609Y C611W C618G C618R C618S C620F ...
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A 5 2IVUA_ZD6
(RET)
TK Vandetanib I 83 291 121
B 2 2IVTA_AMP
(RET)
TK Adenosine mo... I 25 11 78