KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2ITWA_STU (PDB code: 2ITW, chain A)
Number of involved diseases in the family	106

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR, PDPK1, RAF1	43	Link
n/a	Epstein-Barr virus infection	FGR, JAK1, JAK3, MAP3K7, SYK	16	Link
n/a	Measles	FYN, JAK1, JAK2, JAK3, MAP3K7	16	Link
	Melanoma	EGFR, FGFR1, IGF1R, MET, RAF1	40	Link
n/a	Tuberculosis	JAK1, JAK2, RAF1, SRC, SYK	21	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	16	Link
	Leukemia	ABL1, ABL2, JAK2, RAF1	12	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MET, SRC	41	Link
	Lung cancer	ALK, EGFR, PTK2, ROS1	40	Link
n/a	Herpes simplex infection	JAK1, JAK2, MAP3K7	10	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
n/a	Influenza A	JAK1, JAK2, RAF1	10	Link
n/a	Hepatitis C	EGFR, JAK1, RAF1	40	Link
	Gastric cancer	EGFR, FGFR2, MET	39	Link
n/a	Leishmaniasis	JAK1, JAK2, MAP3K7	10	Link
n/a	Toxoplasmosis	JAK1, JAK2, MAP3K7	10	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	SCID	JAK3, LCK	16	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
n/a	Cervical cancer	EGFR, FGFR3	38	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
n/a	Immunodeficiencies	JAK3, LCK	16	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	18	Link
n/a	Alcoholism	NTRK2, RAF1	10	Link
n/a	Choriocarcinoma	CSF1R, EGFR	43	Link
n/a	Shigellosis	ABL1, SRC	20	Link
	Colon cancer	AURKA, SRC	19	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	12	Link
n/a	Bladder cancer	EGFR, FGFR3	38	Link
n/a	Thyroid cancer	NTRK1, RET	18	Link
	Craniosynostosis	FGFR2	8	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
n/a	Agammaglobulinemias	BTK	5	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
	Scaphocephaly	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
n/a	Pituitary Dwarfism	BTK	5	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
n/a	CATSHL syndrome	FGFR3	7	Link
	Adenocarcinoma of lung	EGFR	38	Link
n/a	Oral cancer	EGFR	38	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Glioma	EGFR	38	Link
n/a	Laryngeal cancer	EGFR	38	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
	Agammaglobulinemia	BTK	5	Link
	Kallmann syndrome	FGFR1	9	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	13	Link
	Trigonocephaly	FGFR1	9	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	3	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
n/a	Obesity	NTRK2	9	Link
n/a	Amoebiasis	PTK2	5	Link
	LEOPARD syndrome	RAF1	2	Link
n/a	Insensitivity to pain	NTRK1	15	Link
n/a	Nephronophthisis	NEK8	1	Link
	Hepatocellular carcinoma	MET	8	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
n/a	Myasthenic syndrome	MUSK	5	Link
n/a	Nephronophthisis-medullary cystic kidney disease	NEK8	1	Link
	Noonan syndrome	RAF1	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
n/a	Popliteal pterygium syndrome	RIPK4	1	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Venous malformations	TEK	32	Link
n/a	Rheumatoid arthritis	TEK	32	Link
	Renal agenesis	RET	11	Link
	Pheochromocytoma	RET	11	Link
	Hirschsprung disease	RET	11	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
	Central hypoventilation syndrome	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
n/a	Autism suseptibility	MET	8	Link
n/a	Malaria	MET	8	Link
n/a	Prion diseases	FYN	10	Link
n/a	Malignant pleural mesothelioma	IGF1R	5	Link
n/a	Synovial sarcoma	IGF1R	5	Link
	Insulin-like growth factor I	IGF1R	5	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Nevus	FGFR3	7	Link
n/a	Leprechaunism	INSR	5	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
n/a	Myeloproliferative disorder	JAK2	10	Link
	Thrombocythemia	JAK2	10	Link
	Renal cell carcinoma	MET	8	Link
n/a	Cholangiocarcinoma	MET	8	Link
	Myelofibrosis	JAK2	10	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Diabetes mellitus	INSR	5	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
	Lymphoproliferative syndrome	ITK	6	Link
	Polycythemia vera	JAK2	10	Link

BioXGEM.

KIDFamMap

Allelic Variants