Allelic Variants

There are no related allelic variants
Related diseases of KIF 2C6EA_HPM (PDB code: 2C6E, chain A)
Number of involved diseases in the family 90
Number of AAK1 related diseases 0
All kinase in this family  AAK1
Allelic
Variants
Disease Description Involved kinases
(This family)
Inhibitor of
Involved Kinases
Search
Disease
Prostate cancerCDK2, CHEK2, EGFR, FGFR1,
FGFR2, RAF1
56Link
n/aTuberculosisJAK2, MAPK8, MAPK9, PLK3,
RAF1
11Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCSK, EGFR, MAPK8, MAPK949Link
LeukemiaABL1, JAK2, RAF1, RPS6KB19Link
n/aInfluenza AJAK2, MAPK8, MAPK9, RAF19Link
n/aHepatitis CEGFR, MAPK8, MAPK9, RAF150Link
Lung cancerALK, CDK2, EGFR, PTK253Link
n/aMeaslesCDK2, JAK2, JAK3, PRKCQ15Link
n/aEpstein-Barr virus infectionCDK2, JAK3, MAPK8, MAPK98Link
n/aHerpes simplex infectionCDK2, JAK2, MAPK8, MAPK98Link
n/aToxoplasmosisJAK2, MAPK8, MAPK97Link
Diabetes mellitusMAPK8, MAPK9, PRKCD11Link
MelanomaEGFR, FGFR1, RAF148Link
n/aShigellosisABL1, MAPK8, MAPK96Link
n/aImmunodeficienciesJAK3, LCK54Link
Pfeiffer syndromeFGFR1, FGFR25Link
Crouzon syndromeFGFR2, FGFR35Link
Gastric cancerEGFR, FGFR249Link
n/aBladder cancerEGFR, FGFR345Link
n/aCervical cancerEGFR, FGFR345Link
Jackson-Weiss syndromeFGFR1, FGFR25Link
LADD syndromeFGFR2, FGFR35Link
n/aChagas diseaseMAPK8, MAPK93Link
n/aPertussisMAPK8, MAPK93Link
SCIDJAK3, LCK54Link
n/aSalmonella infectionMAPK8, MAPK93Link
n/aMedullary thyroid carcinomaRET2Link
Central hypoventilation syndromeRET2Link
n/aEsophageal cancerEGFR45Link
OsteosarcomaCHEK24Link
n/aOral cancerEGFR45Link
n/aCongenital central hypoventilation syndromeRET2Link
Hirschsprung diseaseRET2Link
n/aChoriocarcinomaEGFR45Link
Adenocarcinoma of lungEGFR45Link
Hypogonadotropic hypogonadismFGFR11Link
n/aThyroid cancerRET2Link
n/aRenal agenesis and Renal adysplasiaRET2Link
Breast cancerCHEK24Link
n/aGliomaEGFR45Link
n/aLaryngeal cancerEGFR45Link
Multiple endocrine neoplasiaRET2Link
Li-Fraumeni syndromeCHEK24Link
NeuroblastomaALK4Link
Colon cancerAURKA102Link
Venous malformationsTEK25Link
n/aViral myocarditisABL13Link
n/aPathogenic Escherichia coli infectionABL13Link
n/aRheumatoid arthritisTEK25Link
n/aMaturity onset diabetes of the youngBLK2Link
n/aAgammaglobulinemiasBTK4Link
Renal agenesisRET2Link
PheochromocytomaRET2Link
n/aBasal cell carcinomaSTK362Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK4Link
n/aPituitary DwarfismBTK4Link
AgammaglobulinemiaBTK4Link
TrigonocephalyFGFR11Link
Osteoglophonic dysplasiaFGFR11Link
n/aNevusFGFR31Link
n/aSpermatocytic seminomaFGFR31Link
n/aMuenke syndromeFGFR31Link
n/aHypochondroplasiaFGFR31Link
n/aAchondroplasiaFGFR31Link
Colorectal cancerFGFR31Link
n/aThanatophoric dysplasiaFGFR31Link
Polycythemia veraJAK24Link
n/aMyeloproliferative disorderJAK24Link
ThrombocythemiaJAK24Link
MyelofibrosisJAK24Link
n/aBudd-Chiari syndromeJAK24Link
n/aLeishmaniasisJAK24Link
n/aType I diabetes mellitusPRKCQ8Link
n/aCATSHL syndromeFGFR31Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR31Link
Apert syndromeFGFR24Link
Beare-Stevenson cutis gyrata syndromeFGFR24Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR24Link
LEOPARD syndromeRAF12Link
Noonan syndromeRAF12Link
Kallmann syndromeFGFR11Link
Bent bone dysplasia syndromeFGFR24Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR24Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR24Link
n/aMultiple myelomaFGFR31Link
ScaphocephalyFGFR24Link
n/aSaethre-Chotzen syndromeFGFR24Link
CraniosynostosisFGFR24Link
n/aAlcoholismRAF12Link
n/aAmoebiasisPTK24Link