KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3LCSA_STU (PDB code: 3LCS, chain A)
Number of involved diseases in the family	109
Number of ALK related diseases	2

All kinase in this family ALK

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	CHUK, EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR	40	Link
n/a	Epstein-Barr virus infection	CHUK, FGR, JAK1, JAK3, MAP3K7, SYK, TYK2	16	Link
n/a	Measles	CHUK, FYN, JAK1, JAK2, JAK3, MAP3K7, TYK2	16	Link
n/a	Herpes simplex infection	CHUK, JAK1, JAK2, MAP3K7, TYK2	10	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CHUK, CSK, EGFR, MET, SRC	41	Link
n/a	Toxoplasmosis	CHUK, JAK1, JAK2, MAP3K7, TYK2	10	Link
	Lung cancer	ALK, CHUK, EGFR, PTK2, ROS1	40	Link
	Melanoma	EGFR, FGFR1, IGF1R, MET	40	Link
n/a	Hepatitis C	CHUK, EGFR, JAK1, TYK2	40	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	16	Link
	Leukemia	ABL1, ABL2, CHUK, JAK2	12	Link
n/a	Tuberculosis	JAK1, JAK2, SRC, SYK	21	Link
n/a	Influenza A	JAK1, JAK2, TYK2	10	Link
	Gastric cancer	EGFR, FGFR2, MET	39	Link
n/a	Leishmaniasis	JAK1, JAK2, MAP3K7	10	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
n/a	Shigellosis	ABL1, CHUK, SRC	20	Link
n/a	Immunodeficiencies	JAK3, ZAP70	16	Link
n/a	Cervical cancer	EGFR, FGFR3	38	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	Hemangioma	FLT4, KDR	54	Link
n/a	Bladder cancer	EGFR, FGFR3	38	Link
n/a	Choriocarcinoma	CSF1R, EGFR	43	Link
	Colon cancer	AURKA, SRC	19	Link
n/a	Thyroid cancer	NTRK1, RET	18	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	18	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	12	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
n/a	Pituitary Dwarfism	BTK	5	Link
n/a	Agammaglobulinemias	BTK	5	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
	Craniosynostosis	FGFR2	8	Link
	Kallmann syndrome	FGFR1	9	Link
	Scaphocephaly	FGFR2	8	Link
	Trigonocephaly	FGFR1	9	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Cocoon syndrome	CHUK	6	Link
n/a	Glioma	EGFR	38	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Oral cancer	EGFR	38	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	13	Link
n/a	Chagas disease	CHUK	6	Link
n/a	Laryngeal cancer	EGFR	38	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	3	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
	Cataract	EPHA2	4	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
	Adenocarcinoma of lung	EGFR	38	Link
n/a	Achondroplasia	FGFR3	7	Link
n/a	Multiple myeloma	FGFR3	7	Link
	Hepatocellular carcinoma	MET	8	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
n/a	Myasthenic syndrome	MUSK	5	Link
n/a	Insensitivity to pain	NTRK1	15	Link
n/a	Autism suseptibility	MET	8	Link
n/a	Malaria	MET	8	Link
n/a	46XY sex reversal 6	MAP3K1	1	Link
	Retinitis pigmentosa	MERTK	6	Link
	Renal cell carcinoma	MET	8	Link
n/a	Cholangiocarcinoma	MET	8	Link
n/a	Alcoholism	NTRK2	9	Link
n/a	Obesity	NTRK2	9	Link
	Renal agenesis	RET	11	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	8	Link
	Selective T-cell defect	ZAP70	10	Link
	Pheochromocytoma	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
n/a	Amoebiasis	PTK2	5	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
	Hirschsprung disease	RET	11	Link
	Central hypoventilation syndrome	RET	11	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
	SCID	JAK3	15	Link
	Thrombocythemia	JAK2	10	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Lymphedemas	FLT4	17	Link
n/a	Lymphedema	FLT4	17	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	Nevus	FGFR3	7	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Prion diseases	FYN	10	Link
n/a	Malignant pleural mesothelioma	IGF1R	5	Link
	Polycythemia vera	JAK2	10	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Myelofibrosis	JAK2	10	Link
n/a	Myeloproliferative disorder	JAK2	10	Link
	Lymphoproliferative syndrome	ITK	6	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
n/a	Synovial sarcoma	IGF1R	5	Link
	Insulin-like growth factor I	IGF1R	5	Link
n/a	Leprechaunism	INSR	5	Link
	Diabetes mellitus	INSR	5	Link
	Rabson-Mendenhall syndrome	INSR	5	Link

BioXGEM.

KIDFamMap

Allelic Variants