KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2BMCA_MPY (PDB code: 2BMC, chain A)
Number of involved diseases in the family	107
Number of AURKA related diseases	1

All kinase in this family AURKA

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	CDC2, CDK2, CSNK2A1, CSNK2A2, GSK3B, JAK1, JAK3, MAP2K4, MAPK10, MAPK8, RIPK1	21	Link
n/a	Measles	CDK2, CDK4, CSNK2A1, CSNK2A2, GSK3B, IRAK4, JAK1, JAK2, JAK3, PRKCQ	37	Link
n/a	Herpes simplex infection	CDC2, CDK2, CSNK2A1, CSNK2A2, JAK1, JAK2, MAPK10, MAPK8	15	Link
n/a	Influenza A	GSK3B, IRAK4, JAK1, JAK2, MAP2K4, MAPK10, MAPK8, RAF1	9	Link
n/a	Hepatitis C	EGFR, GSK3B, JAK1, MAPK10, MAPK8, RAF1, RIPK1	10	Link
n/a	Tuberculosis	CAMK2A, IRAK4, JAK1, JAK2, MAPK10, MAPK8, RAF1	3	Link
	Prostate cancer	CDK2, EGFR, FGFR1, FGFR2, GSK3B, PDPK1, RAF1	36	Link
	Leukemia	ABL1, ABL2, CDK4, JAK2, RAF1, RPS6KB1	26	Link
	Lung cancer	ALK, CDK2, CDK4, EGFR, PTK2	32	Link
n/a	Toxoplasmosis	IRAK4, JAK1, JAK2, MAPK10, MAPK8	2	Link
	Melanoma	CDK4, EGFR, FGFR1, RAF1	29	Link
n/a	Alcoholism	CAMKK1, CAMKK2, NTRK2, RAF1	2	Link
	Diabetes mellitus	MAPK10, MAPK8, PRKCD, PRKCZ	6	Link
n/a	Chagas disease	IRAK4, MAP2K4, MAPK10, MAPK8	1	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	3	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MAP2K4, MAPK10, MAPK8	3	Link
n/a	Pertussis	IRAK4, MAPK10, MAPK8	1	Link
n/a	Salmonella infection	MAPK10, MAPK8, PKN2	1	Link
n/a	Cardiomyopathy	MYLK2, PRKAA1, PRKAA2	1	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2	2	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	11	Link
n/a	Cervical cancer	CDK4, EGFR, FGFR3	23	Link
n/a	Shigellosis	ABL1, MAPK10, MAPK8	4	Link
	Gastric cancer	EGFR, FGFR2	3	Link
	Pfeiffer syndrome	FGFR1, FGFR2	6	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	6	Link
n/a	Viral myocarditis	ABL1, ABL2	4	Link
n/a	Thyroid cancer	NTRK1, RET	3	Link
n/a	Bladder cancer	EGFR, FGFR3	3	Link
	SCID	JAK3, LCK	11	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	3	Link
n/a	Glioma	CDK4, EGFR	23	Link
	LADD syndrome	FGFR2, FGFR3	2	Link
	Crouzon syndrome	FGFR2, FGFR3	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	1	Link
	Trigonocephaly	FGFR1	6	Link
	Bent bone dysplasia syndrome	FGFR2	1	Link
n/a	Pathogenic Escherichia coli infection	ABL1	4	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	1	Link
	Kallmann syndrome	FGFR1	6	Link
	Apert syndrome	FGFR2	1	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	1	Link
	Craniosynostosis	FGFR2	1	Link
	Colon cancer	AURKA	37	Link
	Osteoglophonic dysplasia	FGFR1	6	Link
n/a	Saethre-Chotzen syndrome	FGFR2	1	Link
n/a	Esophageal cancer	EGFR	2	Link
n/a	Oral cancer	EGFR	2	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	1	Link
n/a	Malignant melanoma	CDK4	21	Link
n/a	Cocaine addiction	CDK5	2	Link
n/a	Choriocarcinoma	EGFR	2	Link
n/a	Laryngeal cancer	EGFR	2	Link
n/a	Maturity onset diabetes of the young	BLK	1	Link
	Hypogonadotropic hypogonadism	FGFR1	6	Link
n/a	Agammaglobulinemias	BTK	1	Link
	Adenocarcinoma of lung	EGFR	2	Link
	Agammaglobulinemia	BTK	1	Link
n/a	Pituitary Dwarfism	BTK	1	Link
	Colorectal cancer	FGFR3	2	Link
	Scaphocephaly	FGFR2	1	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	1	Link
	Glycogen storage disease	PHKG2	1	Link
n/a	Type I diabetes mellitus	PRKCQ	2	Link
n/a	Amoebiasis	PTK2	1	Link
n/a	Glycogen storage diseases	PHKG2	1	Link
n/a	Obesity	NTRK2	1	Link
n/a	Epileptic encephalopathy	MAPK10	1	Link
n/a	Familial thoracic aortic aneurysm and dissection	MYLK	1	Link
n/a	Aortic aneurysm	MYLK	1	Link
n/a	Insensitivity to pain	NTRK1	2	Link
	LEOPARD syndrome	RAF1	1	Link
	Noonan syndrome	RAF1	1	Link
	Renal agenesis	RET	2	Link
	Venous malformations	TEK	2	Link
n/a	Rheumatoid arthritis	TEK	2	Link
	Selective T-cell defect	ZAP70	1	Link
	Pheochromocytoma	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
n/a	Early infantile epileptic encephalopathy	MAPK10	1	Link
	Thrombocythemia	JAK2	2	Link
n/a	Muenke syndrome	FGFR3	2	Link
n/a	Nevus	FGFR3	2	Link
n/a	Spermatocytic seminoma	FGFR3	2	Link
n/a	Thanatophoric dysplasia	FGFR3	2	Link
n/a	Hypochondroplasia	FGFR3	2	Link
n/a	Achondroplasia	FGFR3	2	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	1	Link
n/a	Multiple myeloma	FGFR3	2	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	2	Link
n/a	CATSHL syndrome	FGFR3	2	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Congenital stationary night blindness	GRK1	1	Link
	Polycythemia vera	JAK2	2	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	Myelofibrosis	JAK2	2	Link
n/a	Myeloproliferative disorder	JAK2	2	Link
	Lymphoproliferative syndrome	ITK	5	Link
	IRAK4 deficiency	IRAK4	1	Link
n/a	Oguchi disease	GRK1	1	Link
n/a	Basal cell carcinoma	GSK3B	7	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	1	Link
n/a	Invasive pneumococcal disease	IRAK4	1	Link

BioXGEM.

KIDFamMap

Allelic Variants