Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
60 |
Number of JAK2 related diseases |
12 |
All kinase in this family
JAK2
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Prostate cancer | BRAF, CDK2, EGFR, GSK3B, IGF1R, MAP2K1, PDPK1, RAF1 | 25 | Link | | Leukemia | ABL1, BRAF, CDK4, JAK2, KIT, MAP2K1, RAF1 | 29 | Link | | Melanoma | BRAF, CDK4, EGFR, IGF1R, MAP2K1, RAF1 | 9 | Link | n/a | Measles | CDK2, CDK4, GSK3B, JAK2, JAK3 | 36 | Link | | Lung cancer | BRAF, CDK2, CDK4, EGFR | 11 | Link | n/a | Epstein-Barr virus infection | CDC2, CDK2, GSK3B, JAK3 | 29 | Link | n/a | Hepatitis C | BRAF, EGFR, GSK3B, RAF1 | 6 | Link | n/a | Influenza A | GSK3B, JAK2, MAP2K1, RAF1 | 28 | Link | n/a | Alcoholism | BRAF, MAP2K1, RAF1 | 2 | Link | n/a | Herpes simplex infection | CDC2, CDK2, JAK2 | 32 | Link | n/a | Tuberculosis | JAK2, RAF1, SRC | 28 | Link | n/a | Glioma | CDK4, EGFR | 3 | Link | n/a | Cervical cancer | CDK4, EGFR | 3 | Link | | LEOPARD syndrome | BRAF, RAF1 | 2 | Link | | Noonan syndrome | BRAF, RAF1 | 2 | Link | | Adenocarcinoma of lung | BRAF, EGFR | 3 | Link | | Cardiofaciocutaneous syndrome | BRAF, MAP2K1 | 2 | Link | | Colon cancer | AURKA, SRC | 11 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, SRC | 4 | Link | n/a | Shigellosis | ABL1, SRC | 4 | Link | n/a | Thyroid cancer | BRAF, NTRK1 | 2 | Link | n/a | Malignant melanoma | BRAF, CDK4 | 2 | Link | n/a | Immunodeficiencies | JAK3, LCK | 23 | Link | | SCID | JAK3, LCK | 23 | Link | n/a | Noonan syndrome and related disorders | BRAF, MAP2K1 | 2 | Link | n/a | Esophageal cancer | EGFR | 2 | Link | | Colorectal cancer | BRAF | 1 | Link | n/a | Oral cancer | EGFR | 2 | Link | n/a | Pathogenic Escherichia coli infection | ABL1 | 2 | Link | n/a | Viral myocarditis | ABL1 | 2 | Link | | Gastric cancer | EGFR | 2 | Link | n/a | Cocaine addiction | CDK5 | 1 | Link | n/a | Laryngeal cancer | EGFR | 2 | Link | n/a | Bladder cancer | EGFR | 2 | Link | | Gastrointestinal stromal tumor | KIT | 1 | Link | | Piebaldism | KIT | 1 | Link | | Thrombocythemia | JAK2 | 24 | Link | | Myelofibrosis | JAK2 | 24 | Link | n/a | Myeloproliferative disorder | JAK2 | 24 | Link | n/a | Germ cell tumors | KIT | 1 | Link | | Mast cell leukemia | KIT | 1 | Link | n/a | Medullary thyroid carcinoma | NTRK1 | 1 | Link | n/a | Insensitivity to pain | NTRK1 | 1 | Link | | Neuroblastoma | NTRK1 | 1 | Link | | Mastocytosis with associated hematologic disorder | KIT | 1 | Link | n/a | Prion diseases | MAP2K1 | 1 | Link | n/a | Budd-Chiari syndrome | JAK2 | 24 | Link | n/a | Toxoplasmosis | JAK2 | 24 | Link | | Insulin-like growth factor I | IGF1R | 6 | Link | n/a | Synovial sarcoma | IGF1R | 6 | Link | n/a | Malignant pleural mesothelioma | IGF1R | 6 | Link | n/a | Choriocarcinoma | EGFR | 2 | Link | n/a | Basal cell carcinoma | GSK3B | 3 | Link | n/a | Leprechaunism | INSR | 1 | Link | | Rabson-Mendenhall syndrome | INSR | 1 | Link | n/a | Leishmaniasis | JAK2 | 24 | Link | | Polycythemia vera | JAK2 | 24 | Link | | Lymphoproliferative syndrome | ITK | 4 | Link | | Diabetes mellitus | INSR | 1 | Link | | Hyperinsulinemic hypoglycemia | INSR | 1 | Link |
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