Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
101 |
Number of LCK related diseases |
2 |
All kinase in this family
LCK
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
| Prostate cancer | BRAF, EGFR, EPHB2, FGFR1, FGFR2, IGF1R, PDGFRA, PDGFRB, RAF1 | 70 | Link | | Melanoma | BRAF, EGFR, FGFR1, IGF1R, PDGFRA, PDGFRB, RAF1 | 69 | Link | | Leukemia | ABL1, ABL2, BRAF, JAK2, KIT, PDGFRB, RAF1 | 41 | Link | n/a | Tuberculosis | JAK2, MAPK14, PLK3, RAF1, SRC, SYK | 93 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | CSK, EGFR, LYN, MAPK14, SRC | 103 | Link | | Neuroblastoma | ALK, NTRK1, NTRK2, NTRK3 | 11 | Link | n/a | Influenza A | JAK2, MAPK14, PRKCB, RAF1 | 54 | Link | n/a | Hepatitis C | BRAF, EGFR, MAPK14, RAF1 | 69 | Link | n/a | Alcoholism | BRAF, NTRK2, RAF1 | 6 | Link | n/a | Glioma | EGFR, PDGFRA, PDGFRB | 44 | Link | n/a | Thyroid cancer | BRAF, NTRK1, RET | 6 | Link | n/a | Epstein-Barr virus infection | LYN, MAPK14, SYK | 53 | Link | n/a | Leishmaniasis | JAK2, MAPK14, PRKCB | 52 | Link | n/a | Shigellosis | ABL1, MAPK14, SRC | 91 | Link | | Lung cancer | ALK, BRAF, EGFR | 23 | Link | | Noonan syndrome | BRAF, RAF1 | 4 | Link | n/a | Myeloproliferative disorder | JAK2, PDGFRB | 30 | Link | | Gastrointestinal stromal tumor | KIT, PDGFRA | 15 | Link | n/a | Toxoplasmosis | JAK2, MAPK14 | 51 | Link | | Gastric cancer | EGFR, FGFR2 | 19 | Link | n/a | Choriocarcinoma | CSF1R, EGFR | 29 | Link | | LEOPARD syndrome | BRAF, RAF1 | 4 | Link | | Colon cancer | AURKA, SRC | 92 | Link | n/a | Medullary thyroid carcinoma | NTRK1, RET | 6 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 14 | Link | | Adenocarcinoma of lung | BRAF, EGFR | 18 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 14 | Link | n/a | Viral myocarditis | ABL1, ABL2 | 9 | Link | n/a | Esophageal cancer | EGFR | 18 | Link | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 1 | Link | | Kallmann syndrome | FGFR1 | 13 | Link | n/a | Bladder cancer | EGFR | 18 | Link | | Osteoglophonic dysplasia | FGFR1 | 13 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 13 | Link | | Cataract | EPHA2 | 2 | Link | n/a | Laryngeal cancer | EGFR | 18 | Link | n/a | Cervical cancer | EGFR | 18 | Link | | Trigonocephaly | FGFR1 | 13 | Link | n/a | Cocaine addiction | CDK5 | 2 | Link | n/a | Oral cancer | EGFR | 18 | Link | n/a | Noonan syndrome and related disorders | BRAF | 2 | Link | | Cardiofaciocutaneous syndrome | BRAF | 2 | Link | n/a | Malignant melanoma | BRAF | 2 | Link | n/a | Maturity onset diabetes of the young | BLK | 2 | Link | n/a | Pathogenic Escherichia coli infection | ABL1 | 9 | Link | | Fibrodysplasia ossificans progressiva | ACVR1 | 2 | Link | | Colorectal cancer | BRAF | 2 | Link | n/a | Agammaglobulinemias | BTK | 2 | Link | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 15 | Link | n/a | Spondylometaepiphyseal dysplasia | DDR2 | 3 | Link | | Apert syndrome | FGFR2 | 1 | Link | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 2 | Link | n/a | Pituitary Dwarfism | BTK | 2 | Link | | Agammaglobulinemia | BTK | 2 | Link | | Crouzon syndrome | FGFR2 | 1 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 1 | Link | n/a | Congenital myasthenic syndrome | MUSK | 2 | Link | n/a | Myasthenic syndrome | MUSK | 2 | Link | n/a | Insensitivity to pain | NTRK1 | 6 | Link | n/a | Chagas disease | MAPK14 | 51 | Link | n/a | Pertussis | MAPK14 | 51 | Link | n/a | Immunodeficiencies | LCK | 46 | Link | | SCID | LCK | 46 | Link | n/a | Amyotrophic lateral sclerosis | MAPK14 | 51 | Link | n/a | Salmonella infection | MAPK14 | 51 | Link | n/a | Obesity | NTRK2 | 4 | Link | n/a | Hypereosinophilic syndrome | PDGFRA | 7 | Link | | Central hypoventilation syndrome | RET | 2 | Link | | Multiple endocrine neoplasia | RET | 2 | Link | | Pheochromocytoma | RET | 2 | Link | | Renal agenesis | RET | 2 | Link | n/a | Congenital central hypoventilation syndrome | RET | 2 | Link | | Hirschsprung disease | RET | 2 | Link | n/a | Vibrio cholerae infection | PRKCB | 1 | Link | n/a | African trypanosomiasis | PRKCB | 1 | Link | n/a | Amoebiasis | PRKCB | 1 | Link | n/a | Renal agenesis and Renal adysplasia | RET | 2 | Link | | Mastocytosis with associated hematologic disorder | KIT | 15 | Link | | Mast cell leukemia | KIT | 15 | Link | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 1 | Link | n/a | Malignant pleural mesothelioma | IGF1R | 14 | Link | n/a | Synovial sarcoma | IGF1R | 14 | Link | | Insulin-like growth factor I | IGF1R | 14 | Link | | Scaphocephaly | FGFR2 | 1 | Link | n/a | Saethre-Chotzen syndrome | FGFR2 | 1 | Link | | Bent bone dysplasia syndrome | FGFR2 | 1 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 1 | Link | | Craniosynostosis | FGFR2 | 1 | Link | | LADD syndrome | FGFR2 | 1 | Link | n/a | Leprechaunism | INSR | 7 | Link | | Rabson-Mendenhall syndrome | INSR | 7 | Link | | Myelofibrosis | JAK2 | 1 | Link | | Thrombocythemia | JAK2 | 1 | Link | | Piebaldism | KIT | 15 | Link | n/a | Germ cell tumors | KIT | 15 | Link | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link | n/a | Herpes simplex infection | JAK2 | 1 | Link | | Diabetes mellitus | INSR | 7 | Link | | Hyperinsulinemic hypoglycemia | INSR | 7 | Link | | Polycythemia vera | JAK2 | 1 | Link | n/a | Measles | JAK2 | 1 | Link |
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