KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2WKMA_PFY (PDB code: 2WKM, chain A)
Number of involved diseases in the family	98
Number of MET related diseases	8

All kinase in this family MET

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	IRAK1, IRAK4, JAK1, JAK2, JAK3, MAP3K7	6	Link
n/a	Toxoplasmosis	IRAK1, IRAK4, JAK1, JAK2, MAP3K7	6	Link
n/a	Leishmaniasis	IRAK1, IRAK4, JAK1, JAK2, MAP3K7	6	Link
n/a	Epstein-Barr virus infection	IRAK1, JAK1, JAK3, MAP3K7	6	Link
	Lung cancer	ALK, EGFR, PTK2, ROS1	17	Link
n/a	Tuberculosis	IRAK1, IRAK4, JAK1, JAK2	6	Link
	Prostate cancer	EGFR, FGFR1, FGFR2	17	Link
	Melanoma	EGFR, FGFR1, MET	22	Link
n/a	Influenza A	IRAK4, JAK1, JAK2	6	Link
	Gastric cancer	EGFR, FGFR2, MET	20	Link
n/a	Herpes simplex infection	JAK1, JAK2, MAP3K7	6	Link
	Neuroblastoma	ALK, NTRK2, NTRK3	7	Link
n/a	Hepatitis C	EGFR, JAK1	14	Link
n/a	Chagas disease	IRAK1, IRAK4	5	Link
	LADD syndrome	FGFR2, FGFR3	5	Link
	Hemangioma	FLT4, KDR	21	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
n/a	Pertussis	IRAK1, IRAK4	5	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	Crouzon syndrome	FGFR2, FGFR3	5	Link
n/a	Choriocarcinoma	CSF1R, EGFR	17	Link
n/a	Cervical cancer	EGFR, FGFR3	16	Link
n/a	Bladder cancer	EGFR, FGFR3	16	Link
	Leukemia	ABL1, JAK2	7	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MET	19	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	4	Link
	Apert syndrome	FGFR2	4	Link
n/a	Multiple myeloma	FGFR3	5	Link
n/a	Pathogenic Escherichia coli infection	ABL1	6	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	5	Link
	Bent bone dysplasia syndrome	FGFR2	4	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	4	Link
	Scaphocephaly	FGFR2	4	Link
n/a	Saethre-Chotzen syndrome	FGFR2	4	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	4	Link
	Craniosynostosis	FGFR2	4	Link
n/a	Agammaglobulinemias	BTK	1	Link
n/a	Shigellosis	ABL1	6	Link
	Agammaglobulinemia	BTK	1	Link
	Adenocarcinoma of lung	EGFR	13	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	1	Link
n/a	Laryngeal cancer	EGFR	13	Link
n/a	Oral cancer	EGFR	13	Link
n/a	Esophageal cancer	EGFR	13	Link
n/a	Glioma	EGFR	13	Link
	Hypogonadotropic hypogonadism	FGFR1	8	Link
	Osteoglophonic dysplasia	FGFR1	8	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	6	Link
n/a	Viral myocarditis	ABL1	6	Link
n/a	Pituitary Dwarfism	BTK	1	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	4	Link
	Trigonocephaly	FGFR1	8	Link
n/a	CATSHL syndrome	FGFR3	5	Link
	Kallmann syndrome	FGFR1	8	Link
n/a	Nevus	FGFR3	5	Link
n/a	Achondroplasia	FGFR3	5	Link
n/a	Myasthenic syndrome	MUSK	2	Link
n/a	Alcoholism	NTRK2	6	Link
n/a	Obesity	NTRK2	6	Link
n/a	Congenital myasthenic syndrome	MUSK	2	Link
	Hepatocellular carcinoma	MET	8	Link
	Renal cell carcinoma	MET	8	Link
n/a	Cholangiocarcinoma	MET	8	Link
n/a	Malaria	MET	8	Link
n/a	Autism suseptibility	MET	8	Link
n/a	Amoebiasis	PTK2	5	Link
n/a	Thyroid cancer	RET	7	Link
	Pheochromocytoma	RET	7	Link
	Renal agenesis	RET	7	Link
n/a	Popliteal pterygium syndrome	RIPK4	2	Link
	Multiple endocrine neoplasia	RET	7	Link
n/a	Medullary thyroid carcinoma	RET	7	Link
n/a	Renal agenesis and Renal adysplasia	RET	7	Link
	Hirschsprung disease	RET	7	Link
n/a	Congenital central hypoventilation syndrome	RET	7	Link
	Central hypoventilation syndrome	RET	7	Link
	SCID	JAK3	5	Link
n/a	Immunodeficiencies	JAK3	5	Link
n/a	Lymphedemas	FLT4	5	Link
n/a	Lymphedema	FLT4	5	Link
n/a	Leprechaunism	INSR	4	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Thanatophoric dysplasia	FGFR3	5	Link
	Colorectal cancer	FGFR3	5	Link
n/a	Hypochondroplasia	FGFR3	5	Link
n/a	Muenke syndrome	FGFR3	5	Link
n/a	Spermatocytic seminoma	FGFR3	5	Link
	Rabson-Mendenhall syndrome	INSR	4	Link
	Diabetes mellitus	INSR	4	Link
	Myelofibrosis	JAK2	4	Link
n/a	Myeloproliferative disorder	JAK2	4	Link
	Thrombocythemia	JAK2	4	Link
n/a	Budd-Chiari syndrome	JAK2	4	Link
	Polycythemia vera	JAK2	4	Link
	Hyperinsulinemic hypoglycemia	INSR	4	Link
n/a	Invasive pneumococcal disease	IRAK4	4	Link
	IRAK4 deficiency	IRAK4	4	Link
	Lymphoproliferative syndrome	ITK	4	Link

BioXGEM.

KIDFamMap

Allelic Variants