KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1UU8A_BI1 (PDB code: 1UU8, chain A)
Number of involved diseases in the family	65
Number of PDPK1 related diseases	1

All kinase in this family PDPK1

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	AKT2, AKT3, CDK2, CDK4, CDK6, CSNK2A1, CSNK2A2, GSK3B, JAK2, JAK3, PRKCQ	105	Link
n/a	Epstein-Barr virus infection	AKT2, AKT3, CDC2, CDK2, CSNK2A1, CSNK2A2, GSK3B, JAK3, MAPK14, PRKACA, PRKACB	87	Link
	Leukemia	AKT2, AKT3, CDK4, CDK6, JAK2, PIM1, PIM2, RPS6KB1	39	Link
	Prostate cancer	AKT2, AKT3, CDK2, CHEK2, EGFR, GSK3B, PDPK1	89	Link
n/a	Influenza A	AKT2, AKT3, GSK3B, JAK2, MAPK14, PRKCB	119	Link
	Melanoma	AKT2, AKT3, CDK4, CDK6, EGFR, STK11	30	Link
	Lung cancer	AKT2, AKT3, CDK2, CDK4, CDK6, EGFR	33	Link
n/a	Tuberculosis	AKT2, AKT3, CAMK2A, CAMK2D, JAK2, MAPK14	19	Link
n/a	Hepatitis C	AKT2, AKT3, EGFR, GSK3B, MAPK14	77	Link
n/a	Herpes simplex infection	CDC2, CDK2, CSNK2A1, CSNK2A2, JAK2	22	Link
n/a	Toxoplasmosis	AKT2, AKT3, JAK2, MAPK14	10	Link
n/a	Chagas disease	AKT2, AKT3, MAPK14	8	Link
	Mental retardation	DYRK1A, PAK3, RPS6KA3	9	Link
n/a	Amoebiasis	PRKACA, PRKACB, PRKCB	89	Link
n/a	Leishmaniasis	JAK2, MAPK14, PRKCB	93	Link
n/a	Vibrio cholerae infection	PRKACA, PRKACB, PRKCB	89	Link
	Diabetes mellitus	AKT2, PRKCD, PRKCZ	45	Link
n/a	Cardiomyopathy	PRKAA2, PRKACA, PRKACB	3	Link
n/a	Salmonella infection	MAPK14, PKN2	6	Link
n/a	Cocaine addiction	PRKACA, PRKACB	3	Link
n/a	Glioma	CDK4, EGFR	27	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MAPK14	5	Link
n/a	Prion diseases	PRKACA, PRKACB	3	Link
n/a	Non-syndromic X-linked mental retardation	PAK3, RPS6KA3	9	Link
n/a	Cervical cancer	CDK4, EGFR	27	Link
n/a	Bladder cancer	DAPK1, EGFR	2	Link
	Breast cancer	CHEK2	2	Link
	Li-Fraumeni syndrome	CHEK2	2	Link
	Osteosarcoma	CHEK2	2	Link
n/a	Malignant melanoma	CDK4	27	Link
n/a	Epileptic encephalopathy	CDKL5	1	Link
n/a	Familial partial lipodystrophy	AKT2	1	Link
	Hypoinsulinemic hypoglycemia	AKT2	1	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Early infantile epileptic encephalopathy	CDKL5	1	Link
n/a	Laryngeal cancer	EGFR	1	Link
n/a	Oral cancer	EGFR	1	Link
n/a	Alcoholism	PRKACA	3	Link
n/a	Pertussis	MAPK14	4	Link
n/a	Shigellosis	MAPK14	4	Link
	SCID	JAK3	6	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	4	Link
n/a	African trypanosomiasis	PRKCB	87	Link
n/a	Cerebral infarction	PRKCH	32	Link
n/a	Testicular tumor	STK11	1	Link
n/a	Peutz-Jeghers syndrome	STK11	1	Link
n/a	Pancreatic cancer	STK11	1	Link
n/a	Type I diabetes mellitus	PRKCQ	21	Link
n/a	Coffin-Lowry syndrome	RPS6KA3	9	Link
n/a	Immunodeficiencies	JAK3	6	Link
	Thrombocythemia	JAK2	2	Link
	Adenocarcinoma of lung	EGFR	1	Link
	Ovarian cancer	AKT2	1	Link
n/a	Choriocarcinoma	EGFR	1	Link
n/a	Esophageal cancer	EGFR	1	Link
	Gastric cancer	EGFR	1	Link
n/a	Congenital stationary night blindness	GRK1	2	Link
n/a	Oguchi disease	GRK1	2	Link
	Myelofibrosis	JAK2	2	Link
n/a	Myeloproliferative disorder	JAK2	2	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	Polycythemia vera	JAK2	2	Link
n/a	Basal cell carcinoma	GSK3B	73	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link

BioXGEM.

KIDFamMap

Allelic Variants