KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1UU9A_BI3 (PDB code: 1UU9, chain A)
Number of involved diseases in the family	69
Number of PDPK1 related diseases	1

All kinase in this family PDPK1

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	AKT1, AKT2, AKT3, CDC2, CDK2, CSNK2A1, CSNK2A2, GSK3B, JAK3, MAPK14, PRKACA, PRKACB	88	Link
n/a	Measles	AKT1, AKT2, AKT3, CDK2, CDK4, CSNK2A1, CSNK2A2, GSK3B, JAK2, JAK3, PRKCQ	106	Link
	Prostate cancer	AKT1, AKT2, AKT3, CDK2, CHEK2, EGFR, GSK3B, PDPK1	94	Link
	Leukemia	AKT1, AKT2, AKT3, CDK4, JAK2, PIM1, PIM2, RPS6KB1	35	Link
n/a	Influenza A	AKT1, AKT2, AKT3, GSK3B, JAK2, MAPK14, PRKCB	120	Link
n/a	Tuberculosis	AKT1, AKT2, AKT3, CAMK2A, CAMK2D, JAK2, MAPK14	17	Link
	Lung cancer	AKT1, AKT2, AKT3, CDK2, CDK4, EGFR	27	Link
n/a	Hepatitis C	AKT1, AKT2, AKT3, EGFR, GSK3B, MAPK14	81	Link
	Melanoma	AKT1, AKT2, AKT3, CDK4, EGFR, STK11	25	Link
n/a	Herpes simplex infection	CDC2, CDK2, CSNK2A1, CSNK2A2, JAK2	15	Link
n/a	Toxoplasmosis	AKT1, AKT2, AKT3, JAK2, MAPK14	8	Link
n/a	Chagas disease	AKT1, AKT2, AKT3, MAPK14	7	Link
	Diabetes mellitus	AKT2, PRKCD, PRKCZ	41	Link
n/a	Leishmaniasis	JAK2, MAPK14, PRKCB	83	Link
n/a	Cardiomyopathy	PRKAA2, PRKACA, PRKACB	3	Link
	Mental retardation	DYRK1A, PAK3, RPS6KA3	10	Link
n/a	Amoebiasis	PRKACA, PRKACB, PRKCB	83	Link
n/a	Vibrio cholerae infection	PRKACA, PRKACB, PRKCB	83	Link
n/a	Glioma	CDK4, EGFR	20	Link
n/a	Cervical cancer	CDK4, EGFR	20	Link
	Breast cancer	AKT1, CHEK2	4	Link
n/a	Prion diseases	PRKACA, PRKACB	3	Link
	Ovarian cancer	AKT1, AKT2	3	Link
n/a	Non-syndromic X-linked mental retardation	PAK3, RPS6KA3	10	Link
n/a	Salmonella infection	MAPK14, PKN2	3	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MAPK14	2	Link
n/a	Bladder cancer	DAPK1, EGFR	3	Link
n/a	Cocaine addiction	PRKACA, PRKACB	3	Link
n/a	Early infantile epileptic encephalopathy	CDKL5	1	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Epileptic encephalopathy	CDKL5	1	Link
	Li-Fraumeni syndrome	CHEK2	2	Link
	Colorectal cancer	AKT1	2	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Proteus syndrome	AKT1	2	Link
n/a	Schizophrenia	AKT1	2	Link
n/a	Familial partial lipodystrophy	AKT2	1	Link
n/a	Malignant melanoma	CDK4	20	Link
	Hypoinsulinemic hypoglycemia	AKT2	1	Link
	Gastric cancer	EGFR	1	Link
	Osteosarcoma	CHEK2	2	Link
n/a	Pertussis	MAPK14	1	Link
n/a	Shigellosis	MAPK14	1	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	1	Link
n/a	Immunodeficiencies	JAK3	5	Link
	SCID	JAK3	5	Link
n/a	Alcoholism	PRKACA	3	Link
n/a	African trypanosomiasis	PRKCB	81	Link
n/a	Peutz-Jeghers syndrome	STK11	1	Link
n/a	Testicular tumor	STK11	1	Link
n/a	Pancreatic cancer	STK11	1	Link
n/a	Coffin-Lowry syndrome	RPS6KA3	10	Link
n/a	Cerebral infarction	PRKCH	31	Link
n/a	Type I diabetes mellitus	PRKCQ	20	Link
	Thrombocythemia	JAK2	1	Link
n/a	Myeloproliferative disorder	JAK2	1	Link
n/a	Laryngeal cancer	EGFR	1	Link
n/a	Choriocarcinoma	EGFR	1	Link
n/a	PTEN hamartoma tumor syndrome	AKT1	2	Link
n/a	Oral cancer	EGFR	1	Link
n/a	Esophageal cancer	EGFR	1	Link
	Adenocarcinoma of lung	EGFR	1	Link
n/a	Congenital stationary night blindness	GRK1	2	Link
n/a	Budd-Chiari syndrome	JAK2	1	Link
	Myelofibrosis	JAK2	1	Link
	Polycythemia vera	JAK2	1	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link
n/a	Oguchi disease	GRK1	2	Link
n/a	Basal cell carcinoma	GSK3B	78	Link

BioXGEM.

KIDFamMap

Allelic Variants