Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
71 |
| Number of PDPK1 related diseases |
1 |
All kinase in this family
PDPK1
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| n/a | Influenza A | AKT1, EIF2AK2, EIF2AK4,
GSK3B, IRAK4, JAK2, MAPK10,
MAPK9 | 16 | Link | | n/a | Measles | AKT1, EIF2AK2, EIF2AK4,
GSK3B, IRAK4, JAK2, JAK3,
PRKCQ | 20 | Link | | n/a | Epstein-Barr virus infection | AKT1, EIF2AK2, EIF2AK4,
GSK3B, JAK3, LYN, MAPK10,
MAPK9 | 13 | Link | | n/a | Hepatitis C | AKT1, EGFR, EIF2AK2,
EIF2AK4, GSK3B, MAPK10,
MAPK9 | 28 | Link | | n/a | Tuberculosis | AKT1, CAMK2D, IRAK4, JAK2,
MAPK10, MAPK9 | 12 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | CSK, EGFR, LYN, MAPK10,
MAPK9 | 18 | Link | | Prostate cancer | AKT1, EGFR, FGFR2, GSK3B,
PDPK1 | 60 | Link | | n/a | Herpes simplex infection | EIF2AK2, EIF2AK4, JAK2,
MAPK10, MAPK9 | 5 | Link | | n/a | Toxoplasmosis | AKT1, IRAK4, JAK2, MAPK10,
MAPK9 | 12 | Link | | Leukemia | ABL1, ABL2, AKT1, JAK2,
RPS6KB1 | 16 | Link | | n/a | Chagas disease | AKT1, IRAK4, MAPK10, MAPK9 | 10 | Link | | n/a | Pertussis | IRAK4, MAPK10, MAPK9 | 4 | Link | | n/a | Shigellosis | ABL1, MAPK10, MAPK9 | 6 | Link | | n/a | Basal cell carcinoma | GSK3B, STK36 | 5 | Link | | n/a | Leishmaniasis | IRAK4, JAK2 | 5 | Link | | Melanoma | AKT1, EGFR | 24 | Link | | Lung cancer | AKT1, EGFR | 24 | Link | | n/a | Viral myocarditis | ABL1, ABL2 | 7 | Link | | n/a | Salmonella infection | MAPK10, MAPK9 | 2 | Link | | Diabetes mellitus | MAPK10, MAPK9 | 2 | Link | | Gastric cancer | EGFR, FGFR2 | 18 | Link | | n/a | Laryngeal cancer | EGFR | 18 | Link | | n/a | Bladder cancer | EGFR | 18 | Link | | Adenocarcinoma of lung | EGFR | 18 | Link | | n/a | Glioma | EGFR | 18 | Link | | n/a | Cervical cancer | EGFR | 18 | Link | | n/a | Choriocarcinoma | EGFR | 18 | Link | | n/a | Proteus syndrome | AKT1 | 6 | Link | | n/a | Esophageal cancer | EGFR | 18 | Link | | Breast cancer | AKT1 | 6 | Link | | n/a | PTEN hamartoma tumor syndrome | AKT1 | 6 | Link | | n/a | Pathogenic Escherichia coli infection | ABL1 | 6 | Link | | Colorectal cancer | AKT1 | 6 | Link | | Ovarian cancer | AKT1 | 6 | Link | | n/a | Oral cancer | EGFR | 18 | Link | | Colon cancer | AURKA | 3 | Link | | n/a | Schizophrenia | AKT1 | 6 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 1 | Link | | Bent bone dysplasia syndrome | FGFR2 | 1 | Link | | Apert syndrome | FGFR2 | 1 | Link | | n/a | Type I diabetes mellitus | PRKCQ | 4 | Link | | n/a | Thyroid cancer | RET | 3 | Link | | n/a | Epileptic encephalopathy | MAPK10 | 1 | Link | | n/a | Early infantile epileptic encephalopathy | MAPK10 | 1 | Link | | n/a | Immunodeficiencies | JAK3 | 3 | Link | | SCID | JAK3 | 3 | Link | | n/a | Renal agenesis and Renal adysplasia | RET | 3 | Link | | Hirschsprung disease | RET | 3 | Link | | Pheochromocytoma | RET | 3 | Link | | Renal agenesis | RET | 3 | Link | | Multiple endocrine neoplasia | RET | 3 | Link | | n/a | Medullary thyroid carcinoma | RET | 3 | Link | | n/a | Congenital central hypoventilation syndrome | RET | 3 | Link | | Central hypoventilation syndrome | RET | 3 | Link | | Thrombocythemia | JAK2 | 4 | Link | | n/a | Myeloproliferative disorder | JAK2 | 4 | Link | | Jackson-Weiss syndrome | FGFR2 | 1 | Link | | LADD syndrome | FGFR2 | 1 | Link | | Crouzon syndrome | FGFR2 | 1 | Link | | Craniosynostosis | FGFR2 | 1 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 1 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 1 | Link | | Pfeiffer syndrome | FGFR2 | 1 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 1 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 4 | Link | | Myelofibrosis | JAK2 | 4 | Link | | Polycythemia vera | JAK2 | 4 | Link | | IRAK4 deficiency | IRAK4 | 2 | Link | | Scaphocephaly | FGFR2 | 1 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 1 | Link | | n/a | Invasive pneumococcal disease | IRAK4 | 2 | Link |
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