Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
87 |
| Number of PKN1 related diseases |
1 |
All kinase in this family
PKN1
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| n/a | Epstein-Barr virus infection | CDC2, CDK2, CSNK2A2, FGR,
GSK3B, JAK3, MAPK10, MAPK8 | 12 | Link | | n/a | Measles | CDK2, CSNK2A2, FYN, GSK3B,
JAK2, JAK3, PRKCQ | 6 | Link | | n/a | Herpes simplex infection | CDC2, CDK2, CSNK2A2, JAK2,
MAPK10, MAPK8 | 10 | Link | | n/a | Tuberculosis | CAMK2A, JAK2, MAPK10, MAPK8,
SRC | 3 | Link | | n/a | Influenza A | GSK3B, JAK2, MAPK10, MAPK8,
PRKCB | 4 | Link | | Prostate cancer | CDK2, FGFR2, GSK3B, PDPK1 | 4 | Link | | n/a | Salmonella infection | MAPK10, MAPK8, PKN1, PKN2 | 1 | Link | | Diabetes mellitus | MAPK10, MAPK8, PRKCD, PRKCE | 2 | Link | | n/a | Shigellosis | ABL1, MAPK10, MAPK8, SRC | 3 | Link | | Neuroblastoma | NTRK1, NTRK2, NTRK3 | 2 | Link | | n/a | Hepatitis C | GSK3B, MAPK10, MAPK8 | 3 | Link | | Leukemia | ABL1, ABL2, JAK2 | 1 | Link | | n/a | Toxoplasmosis | JAK2, MAPK10, MAPK8 | 1 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | MAPK10, MAPK8, SRC | 3 | Link | | n/a | Viral myocarditis | ABL1, ABL2, FYN | 1 | Link | | n/a | Alcoholism | CAMKK1, CAMKK2, NTRK2 | 1 | Link | | n/a | Leishmaniasis | JAK2, PRKCB | 2 | Link | | n/a | Thyroid cancer | NTRK1, RET | 3 | Link | | n/a | Pertussis | MAPK10, MAPK8 | 1 | Link | | LADD syndrome | FGFR2, FGFR3 | 1 | Link | | n/a | Immunodeficiencies | JAK3, ZAP70 | 1 | Link | | Crouzon syndrome | FGFR2, FGFR3 | 1 | Link | | n/a | Chagas disease | MAPK10, MAPK8 | 1 | Link | | n/a | Pathogenic Escherichia coli infection | ABL1, FYN | 1 | Link | | n/a | Medullary thyroid carcinoma | NTRK1, RET | 3 | Link | | n/a | Achondroplasia | FGFR3 | 1 | Link | | Scaphocephaly | FGFR2 | 1 | Link | | n/a | Cervical cancer | FGFR3 | 1 | Link | | Colorectal cancer | FGFR3 | 1 | Link | | n/a | Hypochondroplasia | FGFR3 | 1 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 1 | Link | | n/a | Multiple myeloma | FGFR3 | 1 | Link | | n/a | Bladder cancer | FGFR3 | 1 | Link | | n/a | Maturity onset diabetes of the young | BLK | 1 | Link | | n/a | FGFR3-related short limb skeletal dysplasias | FGFR3 | 1 | Link | | n/a | CATSHL syndrome | FGFR3 | 1 | Link | | Jackson-Weiss syndrome | FGFR2 | 1 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 1 | Link | | Apert syndrome | FGFR2 | 1 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 1 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 1 | Link | | Gastric cancer | FGFR2 | 1 | Link | | Venous malformations | TEK | 1 | Link | | Lung cancer | CDK2 | 2 | Link | | Bent bone dysplasia syndrome | FGFR2 | 1 | Link | | n/a | Rheumatoid arthritis | TEK | 1 | Link | | Colon cancer | SRC | 3 | Link | | Pfeiffer syndrome | FGFR2 | 1 | Link | | Craniosynostosis | FGFR2 | 1 | Link | | Selective T-cell defect | ZAP70 | 1 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 1 | Link | | n/a | Muenke syndrome | FGFR3 | 1 | Link | | n/a | Congenital stationary night blindness | GRK1 | 1 | Link | | n/a | Nevus | FGFR3 | 1 | Link | | n/a | Vibrio cholerae infection | PRKCB | 1 | Link | | n/a | African trypanosomiasis | PRKCB | 1 | Link | | Glycogen storage disease | PHKG2 | 1 | Link | | n/a | Cirrhosis due to liver phosphorylase kinase deficiency | PHKG2 | 1 | Link | | n/a | Obesity | NTRK2 | 1 | Link | | n/a | Glycogen storage diseases | PHKG2 | 1 | Link | | n/a | Amoebiasis | PRKCB | 1 | Link | | n/a | Cerebral infarction | PRKCH | 1 | Link | | Multiple endocrine neoplasia | RET | 3 | Link | | Pheochromocytoma | RET | 3 | Link | | Central hypoventilation syndrome | RET | 3 | Link | | n/a | Congenital central hypoventilation syndrome | RET | 3 | Link | | n/a | Type I diabetes mellitus | PRKCQ | 3 | Link | | n/a | Renal agenesis and Renal adysplasia | RET | 3 | Link | | Hirschsprung disease | RET | 3 | Link | | n/a | Insensitivity to pain | NTRK1 | 1 | Link | | n/a | Epileptic encephalopathy | MAPK10 | 1 | Link | | n/a | Oguchi disease | GRK1 | 1 | Link | | n/a | Basal cell carcinoma | GSK3B | 3 | Link | | Renal agenesis | RET | 3 | Link | | n/a | Prion diseases | FYN | 1 | Link | | n/a | Spermatocytic seminoma | FGFR3 | 1 | Link | | n/a | Thanatophoric dysplasia | FGFR3 | 1 | Link | | n/a | Cancer progression/metastasis | FGFR4 | 1 | Link | | n/a | Endocrine-cerebroosteodysplasia | ICK | 1 | Link | | Lymphoproliferative syndrome | ITK | 1 | Link | | SCID | JAK3 | 1 | Link | | n/a | Early infantile epileptic encephalopathy | MAPK10 | 1 | Link | | Thrombocythemia | JAK2 | 1 | Link | | n/a | Myeloproliferative disorder | JAK2 | 1 | Link | | Polycythemia vera | JAK2 | 1 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link | | Myelofibrosis | JAK2 | 1 | Link |
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