Allelic Variants

There are no related allelic variants
Related diseases of KIF 3E5AA_VX6 (PDB code: 3E5A, chain A)
Number of involved diseases in the family 93
Number of PKN1 related diseases 1
All kinase in this family  PKN1
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
n/aMeaslesAKT2, CDK2, CHUK, GSK3B,
IRAK4, JAK2, JAK3, PRKCQ		44Link
n/aEpstein-Barr virus infectionAKT2, CDC2, CDK2, CHUK,
GSK3B, JAK3, RIPK1, SYK		23Link
Prostate cancerAKT2, CDK2, CHUK, FGFR1,
FGFR2, GSK3B		23Link
n/aTuberculosisAKT2, IRAK4, JAK2, PLK3, SYK16Link
LeukemiaABL1, ABL2, AKT2, CHUK, JAK221Link
NeuroblastomaALK, NTRK1, NTRK2, NTRK35Link
Lung cancerAKT2, ALK, CDK2, CHUK17Link
n/aInfluenza AAKT2, GSK3B, IRAK4, JAK221Link
n/aHerpes simplex infectionCDC2, CDK2, CHUK, JAK228Link
n/aToxoplasmosisAKT2, CHUK, IRAK4, JAK218Link
n/aHepatitis CAKT2, CHUK, GSK3B, RIPK112Link
n/aChagas diseaseAKT2, CHUK, IRAK45Link
Pfeiffer syndromeFGFR1, FGFR22Link
LADD syndromeFGFR2, FGFR32Link
Jackson-Weiss syndromeFGFR1, FGFR22Link
MelanomaAKT2, FGFR13Link
Diabetes mellitusAKT2, PRKCD10Link
n/aShigellosisABL1, CHUK8Link
n/aViral myocarditisABL1, ABL25Link
n/aLeishmaniasisIRAK4, JAK214Link
Crouzon syndromeFGFR2, FGFR32Link
SCIDJAK3, LCK9Link
n/aSalmonella infectionPKN1, PKN22Link
n/aImmunodeficienciesJAK3, LCK9Link
n/aMedullary thyroid carcinomaNTRK1, RET5Link
n/aThyroid cancerNTRK1, RET5Link
Hypogonadotropic hypogonadismFGFR12Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCHUK3Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK2Link
AgammaglobulinemiaBTK2Link
n/aAgammaglobulinemiasBTK2Link
n/aPituitary DwarfismBTK2Link
n/aCocoon syndromeCHUK3Link
n/aMaturity onset diabetes of the youngBLK2Link
n/aEpileptic encephalopathyCDKL51Link
n/aAngelman syndrome-likeCDKL51Link
n/aEarly infantile epileptic encephalopathyCDKL51Link
n/aCocaine addictionCDK51Link
n/aPrader-Willi and Angelman syndromesCDKL51Link
Colon cancerAURKA64Link
Osteoglophonic dysplasiaFGFR12Link
Multiple endocrine neoplasiaRET3Link
Central hypoventilation syndromeRET3Link
n/aFamilial partial lipodystrophyAKT21Link
Ovarian cancerAKT21Link
n/aPathogenic Escherichia coli infectionABL15Link
Renal agenesisRET3Link
PheochromocytomaRET3Link
n/aCongenital central hypoventilation syndromeRET3Link
Hirschsprung diseaseRET3Link
n/aObesityNTRK23Link
Hypoinsulinemic hypoglycemiaAKT21Link
n/aAlcoholismNTRK23Link
n/aGlycogen storage diseasesPHKG21Link
n/aCirrhosis due to liver phosphorylase kinase deficiencyPHKG21Link
n/aRenal agenesis and Renal adysplasiaRET3Link
n/aType I diabetes mellitusPRKCQ10Link
Glycogen storage diseasePHKG21Link
TrigonocephalyFGFR12Link
n/aMyeloproliferative disorderJAK214Link
n/aSpermatocytic seminomaFGFR32Link
n/aThanatophoric dysplasiaFGFR32Link
n/aNevusFGFR32Link
n/aMuenke syndromeFGFR32Link
Colorectal cancerFGFR32Link
n/aHypochondroplasiaFGFR32Link
n/aCancer progression/metastasisFGFR42Link
n/aBasal cell carcinomaGSK3B6Link
n/aBudd-Chiari syndromeJAK214Link
MyelofibrosisJAK214Link
Polycythemia veraJAK214Link
IRAK4 deficiencyIRAK41Link
n/aPertussisIRAK41Link
ThrombocythemiaJAK214Link
n/aInvasive pneumococcal diseaseIRAK41Link
n/aCervical cancerFGFR32Link
n/aAchondroplasiaFGFR32Link
Beare-Stevenson cutis gyrata syndromeFGFR22Link
Bent bone dysplasia syndromeFGFR22Link
Apert syndromeFGFR22Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR22Link
n/aInsensitivity to painNTRK15Link
Kallmann syndromeFGFR12Link
Gastric cancerFGFR22Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR22Link
CraniosynostosisFGFR22Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR32Link
n/aCATSHL syndromeFGFR32Link
n/aBladder cancerFGFR32Link
n/aMultiple myelomaFGFR32Link
n/aSaethre-Chotzen syndromeFGFR22Link
ScaphocephalyFGFR22Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR22Link