KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3EFWA_AK8 (PDB code: 3EFW, chain A)
Number of involved diseases in the family	105
Number of PRKAA1 related diseases	1

All kinase in this family PRKAA1

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	CDK2, EIF2AK2, JAK1, JAK3, MAP2K4, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9, PRKACA, PRKACB, PRKX, RIPK1, SYK	5	Link
n/a	Hepatitis C	BRAF, EGFR, EIF2AK2, JAK1, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9, RAF1, RIPK1	14	Link
n/a	Influenza A	EIF2AK2, JAK1, JAK2, MAP2K4, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9, RAF1	3	Link
n/a	Tuberculosis	JAK1, JAK2, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9, PLK3, RAF1, SYK	3	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MAP2K4, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
	Prostate cancer	BRAF, CDK2, CHEK2, EGFR, FGFR1, FGFR2, RAF1	13	Link
n/a	Herpes simplex infection	CDK2, EIF2AK2, JAK1, JAK2, MAPK10, MAPK8, MAPK9	3	Link
n/a	Toxoplasmosis	JAK1, JAK2, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
	Leukemia	ABL1, ABL2, BRAF, CDK4, JAK2, RAF1, RPS6KB1	15	Link
n/a	Measles	CDK2, CDK4, EIF2AK2, JAK1, JAK2, JAK3, PRKCQ	4	Link
n/a	Chagas disease	MAP2K4, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
n/a	Shigellosis	ABL1, MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	5	Link
	Lung cancer	ALK, BRAF, CDK2, CDK4, EGFR, PTK2	13	Link
n/a	Alcoholism	BRAF, CAMKK1, CAMKK2, NTRK2, PRKACA, RAF1	13	Link
	Melanoma	BRAF, CDK4, EGFR, FGFR1, RAF1	13	Link
n/a	Pertussis	MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
n/a	Salmonella infection	MAPK10, MAPK12, MAPK13, MAPK8, MAPK9	3	Link
n/a	Cardiomyopathy	MYLK2, PRKAA1, PRKACA, PRKACB, PRKX	2	Link
n/a	Cocaine addiction	CDK5, PRKACA, PRKACB, PRKX	2	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	2	Link
n/a	Leishmaniasis	JAK1, JAK2, MAPK12, MAPK13	2	Link
n/a	Amoebiasis	PRKACA, PRKACB, PRKX, PTK2	3	Link
n/a	Vibrio cholerae infection	PRKACA, PRKACB, PRKX	2	Link
n/a	Cervical cancer	CDK4, EGFR, FGFR3	2	Link
n/a	Prion diseases	PRKACA, PRKACB, PRKX	2	Link
	Diabetes mellitus	MAPK10, MAPK8, MAPK9	3	Link
n/a	Thyroid cancer	BRAF, NTRK1, RET	13	Link
n/a	Early infantile epileptic encephalopathy	CDKL5, MAPK10	3	Link
n/a	Malignant melanoma	BRAF, CDK4	13	Link
n/a	Viral myocarditis	ABL1, ABL2	4	Link
	LADD syndrome	FGFR2, FGFR3	2	Link
n/a	Glioma	CDK4, EGFR	2	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	2	Link
	Pfeiffer syndrome	FGFR1, FGFR2	2	Link
n/a	Bladder cancer	EGFR, FGFR3	2	Link
	Crouzon syndrome	FGFR2, FGFR3	2	Link
	Gastric cancer	EGFR, FGFR2	2	Link
n/a	Epileptic encephalopathy	CDKL5, MAPK10	3	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	2	Link
	LEOPARD syndrome	BRAF, RAF1	13	Link
	Colorectal cancer	BRAF, FGFR3	13	Link
n/a	Immunodeficiencies	JAK3, LCK	13	Link
	Adenocarcinoma of lung	BRAF, EGFR	13	Link
	SCID	JAK3, LCK	13	Link
	Noonan syndrome	BRAF, RAF1	13	Link
n/a	Amyotrophic lateral sclerosis	MAPK12, MAPK13	2	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
	Li-Fraumeni syndrome	CHEK2	1	Link
n/a	Choriocarcinoma	EGFR	2	Link
n/a	Laryngeal cancer	EGFR	2	Link
n/a	Pathogenic Escherichia coli infection	ABL1	4	Link
n/a	Noonan syndrome and related disorders	BRAF	13	Link
	Hypogonadotropic hypogonadism	FGFR1	2	Link
	Cardiofaciocutaneous syndrome	BRAF	13	Link
	Colon cancer	AURKA	8	Link
	Osteosarcoma	CHEK2	1	Link
	Breast cancer	CHEK2	1	Link
	Osteoglophonic dysplasia	FGFR1	2	Link
n/a	Oral cancer	EGFR	2	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
n/a	Esophageal cancer	EGFR	2	Link
	Craniosynostosis	FGFR2	2	Link
	Trigonocephaly	FGFR1	2	Link
n/a	Short rib-polydactyly syndorme	NEK1	1	Link
n/a	Insensitivity to pain	NTRK1	2	Link
n/a	Obesity	NTRK2	2	Link
	REtinitis pigmentosa	MAK	1	Link
	Thrombocythemia	JAK2	2	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	Myelofibrosis	JAK2	2	Link
n/a	Myeloproliferative disorder	JAK2	2	Link
n/a	Type I diabetes mellitus	PRKCQ	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
n/a	Basal cell carcinoma	STK36	2	Link
	Venous malformations	TEK	35	Link
n/a	Rheumatoid arthritis	TEK	35	Link
	Renal agenesis	RET	2	Link
	Pheochromocytoma	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
	Polycythemia vera	JAK2	2	Link
	Lymphoproliferative syndrome	ITK	2	Link
n/a	Saethre-Chotzen syndrome	FGFR2	2	Link
	Scaphocephaly	FGFR2	2	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	2	Link
	Bent bone dysplasia syndrome	FGFR2	2	Link
	Kallmann syndrome	FGFR1	2	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	2	Link
	Apert syndrome	FGFR2	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	2	Link
n/a	Multiple myeloma	FGFR3	1	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	1	Link
n/a	Thanatophoric dysplasia	FGFR3	1	Link
n/a	Cancer progression/metastasis	FGFR4	2	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	1	Link
n/a	Spermatocytic seminoma	FGFR3	1	Link
n/a	Nevus	FGFR3	1	Link
n/a	CATSHL syndrome	FGFR3	1	Link
n/a	Achondroplasia	FGFR3	1	Link
n/a	Hypochondroplasia	FGFR3	1	Link
n/a	Muenke syndrome	FGFR3	1	Link

BioXGEM.

KIDFamMap

Allelic Variants