KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1XJDA_STU (PDB code: 1XJD, chain A)
Number of involved diseases in the family	106
Number of PRKCQ related diseases	2

All kinase in this family PRKCQ

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Tuberculosis	AKT2, AKT3, CAMK2A, CAMK2D, CAMK2G, JAK2, MAPK10, MAPK12, MAPK8, PLK3, RAF1, SRC, SYK	22	Link
n/a	Epstein-Barr virus infection	AKT2, AKT3, CDC2, CDK2, CSNK2A2, FGR, GSK3B, JAK3, MAPK10, MAPK12, MAPK8, SYK	19	Link
n/a	Measles	AKT2, AKT3, CDK2, CDK6, CSNK2A2, FYN, GSK3B, JAK2, JAK3, PRKCQ	18	Link
n/a	Influenza A	AKT2, AKT3, GSK3B, JAK2, MAPK10, MAPK12, MAPK8, PRKCA, PRKCB, RAF1	61	Link
	Prostate cancer	AKT2, AKT3, CDK2, CHEK2, FGFR2, GSK3B, PDPK1, RAF1	15	Link
	Leukemia	ABL1, ABL2, AKT2, AKT3, CDK6, JAK2, PIM2, RAF1	13	Link
n/a	Hepatitis C	AKT2, AKT3, GSK3B, MAPK10, MAPK12, MAPK8, RAF1	11	Link
n/a	Salmonella infection	MAPK10, MAPK12, MAPK8, PKN1, PKN2, ROCK1, ROCK2	13	Link
n/a	Shigellosis	ABL1, MAPK10, MAPK12, MAPK8, ROCK1, ROCK2, SRC	22	Link
n/a	Herpes simplex infection	CDC2, CDK2, CSNK2A2, JAK2, MAPK10, MAPK8	15	Link
n/a	Toxoplasmosis	AKT2, AKT3, JAK2, MAPK10, MAPK12, MAPK8	11	Link
n/a	Chagas disease	AKT2, AKT3, MAPK10, MAPK12, MAPK8	8	Link
	Diabetes mellitus	AKT2, MAPK10, MAPK8, PRKCD, PRKCE	15	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, MAPK10, MAPK12, MAPK8, SRC	21	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA, ROCK1, ROCK2	61	Link
n/a	Alcoholism	CAMKK1, CAMKK2, NTRK2, RAF1	11	Link
	Melanoma	AKT2, AKT3, CDK6, RAF1	8	Link
	Lung cancer	AKT2, AKT3, CDK2, CDK6	12	Link
	Neuroblastoma	NTRK1, NTRK2, NTRK3	15	Link
n/a	Leishmaniasis	JAK2, MAPK12, PRKCB	14	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
n/a	Pertussis	MAPK10, MAPK12, MAPK8	7	Link
n/a	Bladder cancer	DAPK1, FGFR3	9	Link
n/a	Immunodeficiencies	JAK3, ZAP70	16	Link
n/a	Early infantile epileptic encephalopathy	CDKL5, MAPK10	6	Link
n/a	Epileptic encephalopathy	CDKL5, MAPK10	6	Link
n/a	Basal cell carcinoma	GSK3B, STK36	10	Link
n/a	Thyroid cancer	NTRK1, RET	18	Link
	Colon cancer	AURKA, SRC	19	Link
	Mental retardation	CASK, DYRK1A	7	Link
n/a	African trypanosomiasis	PRKCA, PRKCB	55	Link
n/a	Amoebiasis	PRKCA, PRKCB	55	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
n/a	Vibrio cholerae infection	PRKCA, PRKCB	55	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	18	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	Gastric cancer	FGFR2	8	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Pfeiffer syndrome	FGFR2	8	Link
	Craniosynostosis	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
	Jackson-Weiss syndrome	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Myotonic dystrophy	DMPK	7	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
	Hypoinsulinemic hypoglycemia	AKT2	7	Link
	Ovarian cancer	AKT2	7	Link
n/a	Familial partial lipodystrophy	AKT2	7	Link
n/a	FG syndrome	CASK	1	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
	Osteosarcoma	CHEK2	5	Link
	Breast cancer	CHEK2	5	Link
	Li-Fraumeni syndrome	CHEK2	5	Link
n/a	Cocaine addiction	CDK5	5	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Achondroplasia	FGFR3	7	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Pituitary tumor	PRKCA	55	Link
n/a	Cerebral infarction	PRKCH	12	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
	LEOPARD syndrome	RAF1	2	Link
	Glycogen storage disease	PHKG2	9	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	9	Link
n/a	Amyotrophic lateral sclerosis	MAPK12	3	Link
n/a	Insensitivity to pain	NTRK1	15	Link
n/a	Obesity	NTRK2	9	Link
n/a	Glycogen storage diseases	PHKG2	9	Link
	Noonan syndrome	RAF1	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Venous malformations	TEK	32	Link
n/a	Rheumatoid arthritis	TEK	32	Link
	Selective T-cell defect	ZAP70	10	Link
	Renal agenesis	RET	11	Link
	Pheochromocytoma	RET	11	Link
	Hirschsprung disease	RET	11	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
	Central hypoventilation syndrome	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
	REtinitis pigmentosa	MAK	1	Link
	SCID	JAK3	15	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Nevus	FGFR3	7	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Cervical cancer	FGFR3	7	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Myelofibrosis	JAK2	10	Link
n/a	Myeloproliferative disorder	JAK2	10	Link
	Thrombocythemia	JAK2	10	Link
	Polycythemia vera	JAK2	10	Link
	Lymphoproliferative syndrome	ITK	6	Link
n/a	Prion diseases	FYN	10	Link
n/a	Congenital stationary night blindness	GRK1	4	Link
n/a	Oguchi disease	GRK1	4	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link

BioXGEM.

KIDFamMap

Allelic Variants