KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1UVRA_BI8 (PDB code: 1UVR, chain A)
Number of involved diseases in the family	65
Number of RPS6KA2 related diseases	0

All kinase in this family RPS6KA2

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	AKT2, AKT3, CDC2, CDK2, CSNK2A1, CSNK2A2, GSK3B, JAK3, MAPK14, PRKACA, PRKACB	87	Link
n/a	Measles	AKT2, AKT3, CDK2, CDK4, CSNK2A1, CSNK2A2, GSK3B, JAK2, JAK3, PRKCQ	97	Link
	Prostate cancer	AKT2, AKT3, CDK2, CHEK2, EGFR, GSK3B, PDPK1	88	Link
	Leukemia	AKT2, AKT3, CDK4, JAK2, PIM1, PIM2, RPS6KB1	28	Link
n/a	Tuberculosis	AKT2, AKT3, CAMK2A, CAMK2D, JAK2, MAPK14	20	Link
n/a	Influenza A	AKT2, AKT3, GSK3B, JAK2, MAPK14, PRKCB	122	Link
n/a	Herpes simplex infection	CDC2, CDK2, CSNK2A1, CSNK2A2, JAK2	13	Link
	Melanoma	AKT2, AKT3, CDK4, EGFR, STK11	19	Link
	Lung cancer	AKT2, AKT3, CDK2, CDK4, EGFR	21	Link
n/a	Hepatitis C	AKT2, AKT3, EGFR, GSK3B, MAPK14	82	Link
n/a	Toxoplasmosis	AKT2, AKT3, JAK2, MAPK14	11	Link
	Mental retardation	DYRK1A, PAK3, RPS6KA3	9	Link
n/a	Vibrio cholerae infection	PRKACA, PRKACB, PRKCB	83	Link
	Diabetes mellitus	AKT2, PRKCD, PRKCZ	43	Link
n/a	Chagas disease	AKT2, AKT3, MAPK14	10	Link
n/a	Leishmaniasis	JAK2, MAPK14, PRKCB	88	Link
n/a	Amoebiasis	PRKACA, PRKACB, PRKCB	83	Link
n/a	Cardiomyopathy	PRKAA2, PRKACA, PRKACB	3	Link
n/a	Bladder cancer	DAPK1, EGFR	2	Link
n/a	Glioma	CDK4, EGFR	16	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MAPK14	7	Link
n/a	Cervical cancer	CDK4, EGFR	16	Link
n/a	Salmonella infection	MAPK14, PKN2	8	Link
n/a	Prion diseases	PRKACA, PRKACB	3	Link
n/a	Non-syndromic X-linked mental retardation	PAK3, RPS6KA3	9	Link
n/a	Cocaine addiction	PRKACA, PRKACB	3	Link
	Li-Fraumeni syndrome	CHEK2	2	Link
	Osteosarcoma	CHEK2	2	Link
	Breast cancer	CHEK2	2	Link
n/a	Epileptic encephalopathy	CDKL5	1	Link
n/a	Familial partial lipodystrophy	AKT2	1	Link
	Hypoinsulinemic hypoglycemia	AKT2	1	Link
n/a	Malignant melanoma	CDK4	16	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Early infantile epileptic encephalopathy	CDKL5	1	Link
n/a	Laryngeal cancer	EGFR	1	Link
n/a	Oral cancer	EGFR	1	Link
n/a	Alcoholism	PRKACA	3	Link
n/a	Pertussis	MAPK14	6	Link
n/a	Shigellosis	MAPK14	6	Link
	SCID	JAK3	5	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	6	Link
n/a	African trypanosomiasis	PRKCB	81	Link
n/a	Cerebral infarction	PRKCH	32	Link
n/a	Testicular tumor	STK11	1	Link
n/a	Peutz-Jeghers syndrome	STK11	1	Link
n/a	Pancreatic cancer	STK11	1	Link
n/a	Type I diabetes mellitus	PRKCQ	18	Link
n/a	Coffin-Lowry syndrome	RPS6KA3	9	Link
n/a	Immunodeficiencies	JAK3	5	Link
	Thrombocythemia	JAK2	1	Link
	Adenocarcinoma of lung	EGFR	1	Link
	Ovarian cancer	AKT2	1	Link
n/a	Choriocarcinoma	EGFR	1	Link
n/a	Esophageal cancer	EGFR	1	Link
	Gastric cancer	EGFR	1	Link
n/a	Congenital stationary night blindness	GRK1	2	Link
n/a	Oguchi disease	GRK1	2	Link
	Myelofibrosis	JAK2	1	Link
n/a	Myeloproliferative disorder	JAK2	1	Link
n/a	Budd-Chiari syndrome	JAK2	1	Link
	Polycythemia vera	JAK2	1	Link
n/a	Basal cell carcinoma	GSK3B	76	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link

BioXGEM.

KIDFamMap

Allelic Variants