Allelic Variants

There are no related allelic variants
Related diseases of KIF 2C0IA_L1G (PDB code: 2C0I, chain A)
Number of involved diseases in the family 86
Number of RPS6KA2 related diseases 0
All kinase in this family  RPS6KA2
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
Prostate cancerBRAF, CDK2, EGFR, EPHB2,
ERBB2, IGF1R, PDGFRA,
PDGFRB, RAF1		98Link
n/aTuberculosisIRAK1, IRAK4, JAK2, MAPK14,
PLK3, RAF1, SRC, SYK		86Link
LeukemiaABL1, ABL2, BRAF, JAK2, KIT,
PDGFRB, RAF1		30Link
n/aMeaslesCDK2, FYN, IRAK1, IRAK4,
JAK2, JAK3		22Link
MelanomaBRAF, EGFR, IGF1R, PDGFRA,
PDGFRB, RAF1		87Link
n/aEpstein-Barr virus infectionCDK2, IRAK1, JAK3, LYN,
MAPK14, SYK		76Link
Lung cancerALK, BRAF, CDK2, EGFR, PTK247Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCSK, EGFR, LYN, MAPK14, SRC102Link
n/aToxoplasmosisIRAK1, IRAK4, JAK2, MAPK1453Link
n/aInfluenza AIRAK4, JAK2, MAPK14, RAF151Link
NeuroblastomaALK, NTRK1, NTRK2, NTRK37Link
n/aHepatitis CBRAF, EGFR, MAPK14, RAF171Link
n/aLeishmaniasisIRAK1, IRAK4, JAK2, MAPK1453Link
n/aBladder cancerDAPK1, EGFR, ERBB228Link
n/aGliomaEGFR, PDGFRA, PDGFRB36Link
n/aPertussisIRAK1, IRAK4, MAPK1449Link
n/aShigellosisABL1, MAPK14, SRC82Link
n/aChagas diseaseIRAK1, IRAK4, MAPK1449Link
n/aViral myocarditisABL1, ABL2, FYN11Link
n/aChoriocarcinomaCSF1R, EGFR, ERBB232Link
Adenocarcinoma of lungBRAF, EGFR, ERBB228Link
n/aAlcoholismBRAF, NTRK2, RAF14Link
n/aThyroid cancerBRAF, NTRK1, RET6Link
n/aPathogenic Escherichia coli infectionABL1, FYN11Link
Noonan syndromeBRAF, RAF12Link
LEOPARD syndromeBRAF, RAF12Link
n/aCervical cancerEGFR, ERBB228Link
Gastric cancerEGFR, ERBB228Link
n/aMedullary thyroid carcinomaNTRK1, RET6Link
n/aMyeloproliferative disorderJAK2, PDGFRB17Link
SCIDJAK3, LCK85Link
n/aImmunodeficienciesJAK3, LCK85Link
n/aHerpes simplex infectionCDK2, JAK216Link
Gastrointestinal stromal tumorKIT, PDGFRA17Link
Endometrial CancerERBB216Link
n/aPancreatic cancerERBB216Link
n/aLaryngeal cancerEGFR27Link
n/aEsophageal cancerEGFR27Link
n/aOral cancerEGFR27Link
n/aLeukoencephalopathy, diffuse hereditary, with spheroidsCSF1R8Link
n/aSpondylometaepiphyseal dysplasiaDDR23Link
Colorectal cancerBRAF2Link
n/aMaturity onset diabetes of the youngBLK4Link
Cardiofaciocutaneous syndromeBRAF2Link
n/aCocaine addictionCDK53Link
n/aMalignant melanomaBRAF2Link
n/aNoonan syndrome and related disordersBRAF2Link
Ovarian cancerERBB216Link
n/aSynovial sarcomaIGF1R59Link
Breast cancerERBB216Link
n/aInsensitivity to painNTRK16Link
n/aObesityNTRK24Link
n/aMyasthenic syndromeMUSK2Link
n/aCongenital myasthenic syndromeMUSK2Link
Mastocytosis with associated hematologic disorderKIT17Link
n/aAmyotrophic lateral sclerosisMAPK1446Link
n/aSalmonella infectionMAPK1446Link
n/aHypereosinophilic syndromePDGFRA6Link
n/aAmoebiasisPTK211Link
PheochromocytomaRET2Link
Renal agenesisRET2Link
Colon cancerSRC31Link
Multiple endocrine neoplasiaRET2Link
Central hypoventilation syndromeRET2Link
n/aRenal agenesis and Renal adysplasiaRET2Link
Hirschsprung diseaseRET2Link
n/aCongenital central hypoventilation syndromeRET2Link
Mast cell leukemiaKIT17Link
n/aGerm cell tumorsKIT17Link
n/aLeprechaunismINSR12Link
Rabson-Mendenhall syndromeINSR12Link
Insulin-like growth factor IIGF1R59Link
n/aMalignant pleural mesotheliomaIGF1R59Link
n/aCholangiocarcinomaERBB216Link
GlioblastomaERBB216Link
n/aPrion diseasesFYN3Link
Diabetes mellitusINSR12Link
Hyperinsulinemic hypoglycemiaINSR12Link
MyelofibrosisJAK24Link
ThrombocythemiaJAK24Link
PiebaldismKIT17Link
n/aBudd-Chiari syndromeJAK24Link
Polycythemia veraJAK24Link
n/aInvasive pneumococcal diseaseIRAK41Link
IRAK4 deficiencyIRAK41Link
Lymphoproliferative syndromeITK7Link