KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2WIHA_P48 (PDB code: 2WIH, chain A)
Number of involved diseases in the family	105
Number of RPS6KA2 related diseases	0

All kinase in this family RPS6KA2

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	AKT1, AKT2, CDC2, CDK2, CHUK, CSNK2A1, CSNK2A2, FGR, GSK3B, JAK1, JAK3, LYN, MAP2K6, MAP3K7, MAPK10, MAPK14, MAPK8	206	Link
n/a	Measles	AKT1, AKT2, CDK2, CDK4, CHUK, CSNK2A1, CSNK2A2, FYN, GSK3B, IRAK4, JAK1, JAK2, JAK3, MAP3K7, PRKCQ	198	Link
n/a	Influenza A	AKT1, AKT2, GSK3B, IRAK4, JAK1, JAK2, MAP2K1, MAP2K6, MAPK10, MAPK14, MAPK8, PRKCA	112	Link
n/a	Toxoplasmosis	AKT1, AKT2, CHUK, IRAK4, JAK1, JAK2, MAP2K6, MAP3K7, MAPK10, MAPK14, MAPK8	102	Link
n/a	Tuberculosis	AKT1, AKT2, IRAK4, JAK1, JAK2, MAPK10, MAPK14, MAPK8, PLK3, SRC	151	Link
n/a	Herpes simplex infection	CDC2, CDK2, CHUK, CSNK2A1, CSNK2A2, JAK1, JAK2, MAP3K7, MAPK10, MAPK8	135	Link
	Prostate cancer	AKT1, AKT2, CDK2, CHUK, FGFR1, FGFR2, GSK3B, MAP2K1, PDPK1	128	Link
	Leukemia	ABL1, ABL2, AKT1, AKT2, CDK4, CHUK, JAK2, MAP2K1	114	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CHUK, LYN, MAPK10, MAPK14, MAPK8, MET, PAK1, SRC	96	Link
n/a	Hepatitis C	AKT1, AKT2, CHUK, GSK3B, JAK1, MAPK10, MAPK14, MAPK8	79	Link
n/a	Chagas disease	AKT1, AKT2, CHUK, IRAK4, MAPK10, MAPK14, MAPK8	73	Link
n/a	Shigellosis	ABL1, CHUK, MAPK10, MAPK14, MAPK8, ROCK1, SRC	101	Link
	Melanoma	AKT1, AKT2, CDK4, FGFR1, MAP2K1, MET	80	Link
n/a	Salmonella infection	MAPK10, MAPK14, MAPK8, PKN1, PKN2, ROCK1	60	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2, MAP3K7, MAPK14	88	Link
	Lung cancer	AKT1, AKT2, CDK2, CDK4, CHUK	146	Link
n/a	Pertussis	IRAK4, MAPK10, MAPK14, MAPK8	59	Link
	Diabetes mellitus	AKT2, MAPK10, MAPK8, PRKCD	24	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA, ROCK1	21	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	14	Link
n/a	Alcoholism	CAMKK1, MAP2K1, NTRK2	3	Link
n/a	Prion diseases	FYN, MAP2K1	2	Link
	Gastric cancer	FGFR2, MET	7	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	Crouzon syndrome	FGFR2, FGFR3	2	Link
	Colon cancer	AURKA, SRC	108	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	Colorectal cancer	AKT1, FGFR3	13	Link
	Ovarian cancer	AKT1, AKT2	11	Link
n/a	Cervical cancer	CDK4, FGFR3	59	Link
n/a	Epileptic encephalopathy	CDKL5, MAPK10	3	Link
n/a	Early infantile epileptic encephalopathy	CDKL5, MAPK10	3	Link
	LADD syndrome	FGFR2, FGFR3	2	Link
n/a	Immunodeficiencies	JAK3, LCK	42	Link
	SCID	JAK3, LCK	42	Link
	Mental retardation	PAK3, RPS6KA3	2	Link
	Neuroblastoma	NTRK2, NTRK3	3	Link
n/a	Non-syndromic X-linked mental retardation	PAK3, RPS6KA3	2	Link
n/a	Amyotrophic lateral sclerosis	MAP2K6, MAPK14	59	Link
n/a	Malaria	MET	7	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
n/a	Autism suseptibility	MET	7	Link
	Hepatocellular carcinoma	MET	7	Link
	Hypoinsulinemic hypoglycemia	AKT2	11	Link
n/a	Cholangiocarcinoma	MET	7	Link
n/a	Familial partial lipodystrophy	AKT2	11	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Cocaine addiction	CDK5	2	Link
n/a	Glioma	CDK4	57	Link
	Renal cell carcinoma	MET	7	Link
n/a	Malignant melanoma	CDK4	57	Link
n/a	Schizophrenia	AKT1	11	Link
	Cardiofaciocutaneous syndrome	MAP2K1	2	Link
n/a	Amoebiasis	PRKCA	7	Link
n/a	African trypanosomiasis	PRKCA	7	Link
n/a	PTEN hamartoma tumor syndrome	AKT1	11	Link
n/a	Pituitary tumor	PRKCA	7	Link
n/a	Coffin-Lowry syndrome	RPS6KA3	2	Link
n/a	Type I diabetes mellitus	PRKCQ	11	Link
n/a	Vibrio cholerae infection	PRKCA	7	Link
	Glycogen storage disease	PHKG2	1	Link
n/a	Congenital myasthenic syndrome	MUSK	2	Link
n/a	Proteus syndrome	AKT1	11	Link
n/a	Myasthenic syndrome	MUSK	2	Link
	Breast cancer	AKT1	11	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	1	Link
n/a	Glycogen storage diseases	PHKG2	1	Link
n/a	Obesity	NTRK2	3	Link
n/a	Noonan syndrome and related disorders	MAP2K1	2	Link
	IRAK4 deficiency	IRAK4	1	Link
n/a	Hypochondroplasia	FGFR3	2	Link
n/a	Muenke syndrome	FGFR3	2	Link
n/a	Achondroplasia	FGFR3	2	Link
n/a	CATSHL syndrome	FGFR3	2	Link
n/a	Multiple myeloma	FGFR3	2	Link
n/a	Bladder cancer	FGFR3	2	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	2	Link
n/a	Nevus	FGFR3	2	Link
n/a	Spermatocytic seminoma	FGFR3	2	Link
	Lymphoproliferative syndrome	ITK	10	Link
n/a	Invasive pneumococcal disease	IRAK4	1	Link
	Polycythemia vera	JAK2	31	Link
n/a	Basal cell carcinoma	GSK3B	6	Link
n/a	Thanatophoric dysplasia	FGFR3	2	Link
n/a	Cancer progression/metastasis	FGFR4	2	Link
n/a	Budd-Chiari syndrome	JAK2	31	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	2	Link
	Scaphocephaly	FGFR2	2	Link
	Kallmann syndrome	FGFR1	9	Link
	Thrombocythemia	JAK2	31	Link
	Trigonocephaly	FGFR1	9	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
n/a	Cocoon syndrome	CHUK	3	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	2	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	2	Link
	Apert syndrome	FGFR2	2	Link
	Myelofibrosis	JAK2	31	Link
n/a	Saethre-Chotzen syndrome	FGFR2	2	Link
n/a	Myeloproliferative disorder	JAK2	31	Link
	Craniosynostosis	FGFR2	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	2	Link
	Bent bone dysplasia syndrome	FGFR2	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	2	Link

BioXGEM.

KIDFamMap

Allelic Variants