Allelic Variants

There are no related allelic variants
Related diseases of KIF 3PJ3A_04L (PDB code: 3PJ3, chain A)
Number of involved diseases in the family 134
Number of RPS6KA2 related diseases 0
All kinase in this family  RPS6KA2
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
Prostate cancerAKT1, BRAF, EGFR, ERBB2,
FGFR2, IGF1R, INSRR, PDGFRA,
PDGFRB, PDPK1		20Link
n/aEpstein-Barr virus infectionAKT1, CDC2, FGR, JAK1, JAK3,
LYN, RIPK1, SYK, TYK2		13Link
n/aMeaslesAKT1, FYN, IRAK4, JAK1,
JAK2, JAK3, TYK2		8Link
MelanomaAKT1, BRAF, EGFR, IGF1R,
MET, PDGFRA, PDGFRB		15Link
LeukemiaABL1, ABL2, AKT1, BRAF,
JAK2, KIT, PDGFRB		20Link
n/aInfluenza AAKT1, IRAK4, JAK1, JAK2,
PRKCA, TYK2		13Link
n/aHepatitis CAKT1, BRAF, EGFR, JAK1,
RIPK1, TYK2		11Link
n/aTuberculosisAKT1, IRAK4, JAK1, JAK2,
SRC, SYK		10Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCSK, EGFR, LYN, MET, SRC9Link
n/aToxoplasmosisAKT1, IRAK4, JAK1, JAK2,
TYK2		6Link
n/aHerpes simplex infectionCDC2, JAK1, JAK2, TYK27Link
n/aBladder cancerDAPK1, EGFR, ERBB2, FGFR36Link
Lung cancerAKT1, ALK, BRAF, EGFR11Link
NeuroblastomaALK, NTRK1, NTRK2, NTRK31Link
Gastric cancerEGFR, ERBB2, FGFR2, MET6Link
n/aGliomaEGFR, PDGFRA, PDGFRB10Link
n/aThyroid cancerBRAF, NTRK1, RET9Link
Adenocarcinoma of lungBRAF, EGFR, ERBB27Link
n/aCervical cancerEGFR, ERBB2, FGFR36Link
n/aLeishmaniasisIRAK4, JAK1, JAK22Link
n/aChoriocarcinomaCSF1R, EGFR, ERBB28Link
n/aImmunodeficienciesJAK3, LCK, ZAP709Link
Colorectal cancerAKT1, BRAF, FGFR36Link
n/aViral myocarditisABL1, ABL2, FYN9Link
n/aPathogenic Escherichia coli infectionABL1, FYN, PRKCA14Link
Breast cancerAKT1, ERBB26Link
LADD syndromeFGFR2, FGFR31Link
Ovarian cancerAKT1, ERBB26Link
Colon cancerAURKA, SRC16Link
n/aMyeloproliferative disorderJAK2, PDGFRB3Link
Crouzon syndromeFGFR2, FGFR31Link
n/aCholangiocarcinomaERBB2, MET3Link
HemangiomaFLT4, KDR16Link
n/aShigellosisABL1, SRC11Link
n/aChagas diseaseAKT1, IRAK45Link
SCIDJAK3, LCK9Link
Gastrointestinal stromal tumorKIT, PDGFRA7Link
n/aMedullary thyroid carcinomaNTRK1, RET8Link
n/aAlcoholismBRAF, NTRK22Link
Endometrial CancerERBB22Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR21Link
GlioblastomaERBB22Link
n/aMalignant melanomaBRAF1Link
n/aPancreatic cancerERBB22Link
Apert syndromeFGFR21Link
Beare-Stevenson cutis gyrata syndromeFGFR21Link
BrachydactylyBMPR1B1Link
n/aMaturity onset diabetes of the youngBLK1Link
Jackson-Weiss syndromeFGFR21Link
n/aChrondrodysplasiaBMPR1B1Link
Bent bone dysplasia syndromeFGFR21Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR21Link
CraniosynostosisFGFR21Link
n/aNoonan syndrome and related disordersBRAF1Link
n/aLaryngeal cancerEGFR6Link
AgammaglobulinemiaBTK2Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK2Link
n/aPituitary DwarfismBTK2Link
Noonan syndromeBRAF1Link
Pfeiffer syndromeFGFR21Link
n/aAgammaglobulinemiasBTK2Link
n/aProteus syndromeAKT14Link
n/aLeukoencephalopathy, diffuse hereditary, with spheroidsCSF1R4Link
n/aEsophageal cancerEGFR6Link
n/aPTEN hamartoma tumor syndromeAKT14Link
n/aOral cancerEGFR6Link
n/aSpondylometaepiphyseal dysplasiaDDR21Link
LEOPARD syndromeBRAF1Link
Cardiofaciocutaneous syndromeBRAF1Link
n/aSchizophreniaAKT14Link
n/aMultiple myelomaFGFR31Link
n/aSaethre-Chotzen syndromeFGFR21Link
n/aShort rib-polydactyly syndormeNEK11Link
n/aMyasthenic syndromeMUSK1Link
n/aInsensitivity to painNTRK11Link
n/aObesityNTRK21Link
n/aSalmonella infectionPKN11Link
n/aHypereosinophilic syndromePDGFRA5Link
n/aCongenital myasthenic syndromeMUSK1Link
Hepatocellular carcinomaMET1Link
Mastocytosis with associated hematologic disorderKIT6Link
Mast cell leukemiaKIT6Link
Retinitis pigmentosaMERTK1Link
Renal cell carcinomaMET1Link
n/aAutism suseptibilityMET1Link
n/aMalariaMET1Link
n/aVibrio cholerae infectionPRKCA7Link
n/aAfrican trypanosomiasisPRKCA7Link
n/aNon-syndromic X-linked mental retardationRPS6KA31Link
Renal agenesisRET8Link
n/aCoffin-Lowry syndromeRPS6KA31Link
Mental retardationRPS6KA31Link
Selective T-cell defectZAP701Link
n/aTyrosine kinase 2 deficiencyTYK21Link
PheochromocytomaRET8Link
Multiple endocrine neoplasiaRET8Link
n/aPituitary tumorPRKCA7Link
n/aAmoebiasisPRKCA7Link
n/aRenal agenesis and Renal adysplasiaRET8Link
Hirschsprung diseaseRET8Link
Central hypoventilation syndromeRET8Link
n/aCongenital central hypoventilation syndromeRET8Link
n/aGerm cell tumorsKIT6Link
PiebaldismKIT6Link
n/aThanatophoric dysplasiaFGFR31Link
n/aSpermatocytic seminomaFGFR31Link
n/aCancer progression/metastasisFGFR41Link
n/aLymphedemasFLT41Link
n/aPrion diseasesFYN1Link
n/aLymphedemaFLT41Link
n/aNevusFGFR31Link
n/aMuenke syndromeFGFR31Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR21Link
ScaphocephalyFGFR21Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR31Link
n/aCATSHL syndromeFGFR31Link
n/aHypochondroplasiaFGFR31Link
n/aAchondroplasiaFGFR31Link
n/aEndocrine-cerebroosteodysplasiaICK1Link
n/aMalignant pleural mesotheliomaIGF1R2Link
Lymphoproliferative syndromeITK40Link
IRAK4 deficiencyIRAK41Link
Polycythemia veraJAK22Link
n/aBudd-Chiari syndromeJAK22Link
ThrombocythemiaJAK22Link
MyelofibrosisJAK22Link
n/aInvasive pneumococcal diseaseIRAK41Link
n/aPertussisIRAK41Link
Insulin-like growth factor IIGF1R2Link
n/aSynovial sarcomaIGF1R2Link
n/aLeprechaunismINSR8Link
Rabson-Mendenhall syndromeINSR8Link
Hyperinsulinemic hypoglycemiaINSR8Link
Diabetes mellitusINSR8Link