Summary of query kinase
Query kinase STK25 (O00506)
Kinase group STE
Number of inhibitors 47
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 STK25 CHEMBL162 BD50059889 n/a n/a 110 n/a n/a BindingDB BindingDB
1 STK25 Staurosporine Staurosporine n/a n/a 110 n/a n/a NB2008 NB2008
2 STK25 Staurosporine Staurosporine n/a n/a 110 n/a n/a NB2011DRx NB2011DRx
3 STK25 HKI_272 HKI_272 n/a n/a 12 n/a n/a NB2011DRx NB2011DRx
4 STK25 cid_11409972 BD00031085 n/a n/a 1200 n/a n/a BindingDB BindingDB
5 STK25 CHEMBL522892 BD50265677 n/a n/a 1200 n/a n/a BindingDB BindingDB
6 STK25 AST_487 AST_487 n/a n/a 1200 n/a n/a NB2008 NB2008
7 STK25 AST_487 AST_487 n/a n/a 1200 n/a n/a NB2011DRx NB2011DRx
8 STK25 CHIR_258 CHIR_258 n/a n/a 1200 n/a n/a NB2008 NB2008
9 STK25 CHIR_258 CHIR_258 n/a n/a 1200 n/a n/a NB2011DRx NB2011DRx
10 STK25 CHEBI:668343 BD50298227 n/a n/a 1800 n/a n/a BindingDB BindingDB
11 STK25 CHEMBL608533 BD50326053 n/a n/a 1800 n/a n/a BindingDB BindingDB
12 STK25 PKC_412 PKC_412 n/a n/a 1800 n/a n/a NB2008 NB2008
13 STK25 PKC_412 PKC_412 n/a n/a 1800 n/a n/a NB2011DRx NB2011DRx
14 STK25 PD_173955 PD_173955 n/a n/a 2700 n/a n/a NB2011DRx NB2011DRx
15 STK25 SU11248 BD00004814 n/a n/a 290 n/a n/a BindingDB BindingDB
16 STK25 Sunitinib Sunitinib n/a n/a 290 n/a n/a NB2008 NB2008
17 STK25 Sunitinib Sunitinib n/a n/a 290 n/a n/a NB2011DRx NB2011DRx
18 STK25 JNJ_28312141 JNJ_28312141 n/a n/a 3100 n/a n/a NB2011DRx NB2011DRx
19 STK25 CHEBI:259924 BD50119072 n/a n/a 3400 n/a n/a BindingDB BindingDB
20 STK25 Dasatinib Dasatinib n/a n/a 3400 n/a n/a NB2011DRx NB2011DRx
21 STK25 EKB_569 EKB_569 n/a n/a 3400 n/a n/a NB2008 NB2008
22 STK25 cid_10138259 BD00031095 n/a n/a 360 n/a n/a BindingDB BindingDB
23 STK25 JNJ-7706621 BD00006866 n/a n/a 360 n/a n/a BindingDB BindingDB
24 STK25 JNJ_7706621 JNJ_7706621 n/a n/a 360 n/a n/a NB2008 NB2008
25 STK25 SU_14813 SU_14813 n/a n/a 360 n/a n/a NB2008 NB2008
26 STK25 SU_14813 SU_14813 n/a n/a 360 n/a n/a NB2011DRx NB2011DRx
27 STK25 KW_2449 KW_2449 n/a n/a 4300 n/a n/a NB2011DRx NB2011DRx
28 STK25 VX-680 BD00013534 n/a n/a 4800 n/a n/a BindingDB BindingDB
29 STK25 VX_680 VX_680 n/a n/a 4800 n/a n/a NB2008 NB2008
30 STK25 VX_680 VX_680 n/a n/a 4800 n/a n/a NB2011DRx NB2011DRx
31 STK25 EXEL_2880 EXEL_2880 n/a n/a 5700 n/a n/a NB2011DRx NB2011DRx
32 STK25 INCB18424 INCB18424 n/a n/a 6300 n/a n/a NB2011DRx NB2011DRx
33 STK25 CHIR_265 CHIR_265 n/a n/a 6800 n/a n/a NB2011DRx NB2011DRx
34 STK25 TG_101348 TG_101348 n/a n/a 7200 n/a n/a NB2011DRx NB2011DRx
35 STK25 TAE_684 TAE_684 n/a n/a 7700 n/a n/a NB2011DRx NB2011DRx
36 STK25 SKI_606 SKI_606 n/a n/a 900 n/a n/a NB2011DRx NB2011DRx
37 STK25 R406 R406 n/a n/a 9200 n/a n/a NB2011DRx NB2011DRx
38 STK25 CHEMBL603469 BD50308060 n/a n/a 97 n/a n/a BindingDB BindingDB
39 STK25 CEP_701 CEP_701 n/a n/a 97 n/a n/a NB2011DRx NB2011DRx
40 STK25 CAS135897_06_2 CAS135897_06_2 n/a n/a n/a n/a 34.36 NB2011RBC NB2011RBC
41 STK25 CAS380843_75_4 CAS380843_75_4 n/a n/a n/a n/a 10.1 NB2011RBC NB2011RBC
42 STK25 CAS443798_55_8 CAS443798_55_8 n/a n/a n/a n/a 8.18 NB2011RBC NB2011RBC
43 STK25 CAS608512_97_6 CAS608512_97_6 n/a n/a n/a n/a 30.66 NB2011RBC NB2011RBC
44 STK25 CAS62996_74_1 CAS62996_74_1 n/a n/a n/a n/a 3.22 NB2011RBC NB2011RBC
45 STK25 CAS856436_16_3 CAS856436_16_3 n/a n/a n/a n/a 47.19 NB2011RBC NB2011RBC
46 STK25 J60 J60 n/a n/a n/a n/a n/a PDB PDB