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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CMGC CDK2 203
CAMK PIM1 38
CAMK PIM2 132
CAMK PIM3 40
FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIR----EISLLKELN----HPN--IVKLLDVIHTENKLYLVFEF-LHQ--DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLIN-TEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF
YQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVS----SGFSGVIRLLDWFERPDSFVLILER-PEPVQDLFDFIT--ERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGA--LLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHD---------EEIIRGQVFFRQRVS--------------------------SECQHLIRWCLALRPSDRPTFEEIQNHPWM
YRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPG--VIRLLDWFETQEGFMLVLERPLPAQ-DLFDYIT--EKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGA--LLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERD---------QEILEAELHFPAHVS--------------------------PDCCALIRRCLAPKPSSRPSLEEILLDPWM
YQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGATV-PLEVVLLRKVGAAGGARG--VIRLLDWFERPDGFLLVLER-PEPAQDLFDFIT--ERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGA--LLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQD---------EEILRGRLLFRRRVS--------------------------PECQQLIRWCLSLRPSERPSLDQIAAHPWM
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