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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK CHEK1 203
CMGC MAPK14 24
TK NTRK1 510
-W-DLVQTLGEGAYGEVQLAVNR-----VTEEAVAVKIVDMKRAVDCP-ENI-KKEICINKMLNHENVVKFYGHRRE------GNIQYLFLEYCSGGELFDRIEPDI----------------GMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFR-YNNRERLLNK---MCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLA-GELPWDQP--SDSCQEYSDWKEKKTYLNPWKKI--D------------------------SAPLALLHKILVENPSARITIPDIKKDRW-Y
--YQNLSPVGSGAYGSVCAAFDT-----KTGLRVAVKKLSRPFQSIIH-AKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGA-DLNNIVK-CQ----------------KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR------HTDDEMTG---YVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLT-GRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF-
IV--LKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALK-EASE-SARQDFQ-REAELLTMLQHQHIVRFFGVCTE------GRPLLMVFEYMRHGDLNRFLR-SHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDI-Y-S--TDYYRVGGRTMLPIRWMPPESIL-YRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACP------------------------------PEVYAIMRGCWQREPQQRHSIKDVHARL---
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