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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK DAPK2 203
AGC PKN1 615
AGC PKN2 657
AGC PRKCA 339
AGC PRKCE 408
AGC ROCK1 76
AGC ROCK2 92
AGC RPS6KA5 49
CAMK STK33 116
--YDIGEELGSGQFAIVKKCRE---KSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQV-L---HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIP-----HIKLIDFGLAHE--IEDGVEFKNIFGTPEFVAPEIVN----YEPLGLEADMWSIGVITYILLSGASPFLGD----TKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRK--RLT-------IQEALRHPWI--------------
-F-KFLAVLGRGHFGKVLLSEF---RPSGELFAIKALKKGDIVARDEVESLM---CEKRILAAV-TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIH-SDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYV---------KIADFGLCKEG-MGYGDRTSTFCGTPEFLAPEVLT----DTSYTRAVDWWGLGVLLYEMLVGESPFPGD----DEEEVFDSIVNDEVRYPRFLS----AEAIGIMRRLLRRNPER--RLGSS--ERDAEDVKKQPFF--------------
FR--CCAVLGRGHFGKVLLAEY---KNTNEMFAIKALKKGDIVARDEVDSLM---CEKRIFETV-NSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIH-TDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFV---------KIADFGLCKEG-MGYGDRTSTFCGTPEFLAPEVLT----ETSYTRAVDWWGLGVLIYEMLVGESPFPGD----DEEEVFDSIVNDEVRYPRFLS----TEAISIMRRLLRRNPER--RLGAS--EKDAEDVKKHPFF--------------
-F-NFLMVLGKGSFGKVMLADR---KGTEELYAIKILKKDVVIQDDDVECTM---VEKRVLALLDK---PPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHI---------KIADFGMCKEH-MMDGVTTRTFCGTPDYIAPEIIA----YQPYGKSVDWWAYGVLLYEMLAGQPPFDGE----DEDELFQSIMEHNVSYPKSLS----KEAVSVCKGLMTKHPAK--RLG-------C---------GPEGERDVREHAFF
-F-NFIKVLGKGSFGKVMLAEL---KGKDEVYAVKVLKKDVILQDDDVDCTM---TEKRILALARK---HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHC---------KLADFGMCKEG-ILNGVTTTTFCGTPDYIAPEILQ----ELEYGPSVDWWALGVLMYEMMAGQPPFEAD----NEDDLFESILHDDVLYPVWLS----KEAVSILKAFMTKNPHK--RLGCVASQNGEDAIKQHP--FF------------
--YEVVKVIGRGAFGEVQLVRH---KSTRKVYAMKLLSKFEMIKRSDSAFFW---EERDIMAFA-N---SPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS-NYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHL---------KLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNG-------VEEIKRHLFF--------------
--YDVVKVIGRGAFGEVQLVRH---KASQKVYAMKLLSKFEMIKRSDSAFFW---EERDIMAFA-N---SPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS-NYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHL---------KLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYAD----SLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNG-------VEEIRQHPFF--------------
--FELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTR--TERQVLEHIRQ---SPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHV---------VLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVR--GGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMS----ALAKDLIQRLLMKDPKK--RLGCG--PRDADEIKEHLFF--------------
--YTFGRILGKGSFGIVIEATD---KETETKWAIKKVNKEKAGSSAVKLLER----EVNILKSV-K---HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVIS----AHDYSQQCDIWSIGVVMYMLLRGEPPFLAS----SEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAH--RIT-------AKELLDNQWL--------------
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