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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK MAPKAPK2 203
CAMK CHEK1 9
CAMK CHEK2 220
CMGC GSK3B 56
CAMK PRKD1 583
KVT---SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKAR-------R------EVELHWRASQCPHIVRIVDVYENLYAGRKCLL--IVMECLDGG--ELFSRIQD--RGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYT-SKRPNAILKLTDFGFAKE---TTSHNSLTTPCYTPYYVAPEVLG---PEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVS----------------------EEVKMLIRNLLKTEPTQRMTITEFMNHPWI-
--W-DLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENI-KK------EICINKML-NHENVVKFYGHRRE----GNIQY--LFLEYCSGG--ELFDRIE----PDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLD-ERDNL---KISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK--RREFHAEPVDVWSCGIVLTAMLAGELPWDQP---SDSCQEYSDWKEKKTYLNPWKKI--D----------------------SAPLALLHKILVENPSARITIPDIKKDRW-Y
-YI--MSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKL-NHPCIIKIKNFF-D----AEDYY--IVLELMEGG--ELFDKVV----GNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLS-SQEEDCLIKITDFGHSKI---LGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEH---RTQVSLKDQITSGKYNFIPEVWAEVS----------------------EKALDLVKKLLVVDPKARFTTEEALRHPWL-
---YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR------------ELQIMRKL-DHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVA---RHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVL---KLCDFGSAKQ---LVRGEPNVSYICSRYYRAPELIF--GATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF-
-PD----EVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRN------EVAILQNL-HHPGVVNLECMFET----PERVF--VVMEKLHGD--MLEMILS---SEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLA-SADPFPQVKLCDFGFARI---IGEKSFRRSVVGTPAYLAPEVLR---NKGYNRSLDMWSVGVIIYVSLSGTFPFNED------EDIHDQIQNAAFMYPPNPWKEIS----------------------HEAIDLINNLLQVKMRKRYSVDKTLSHPWL-
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