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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
AGC SGK1 203
CMGC CDC2 4
CAMK CHEK2 220
--FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIM-----SERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQ---RERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHI---VLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLH---KQPYDRTVDWWCLGAVLYEMLYGLPPFYSR---NTAEMYDNILNKPLQLKPNIT--------------------------NSARHLLEGLLQKDRTKRLGAKDDFMEIKSHV--FF
--YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIR------EISLL-KELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTI---KLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLL--GSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS----GKMALNHPYF--
YI--MSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEIL-KKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVV---GNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKI-LGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEH--RTQVSLKDQITSGKYNFIPEVWAEVS----------------------EKALDLVKKLLVVDPKARFT----TEEALRHPWL--
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