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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
TKL TGFBR1 203
TK LCK 245
TK SRC 270
IV--LQESIGKGRFGEVWRGKWRGEE--VAVKIFSSREERSWFREA--EIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRY---TVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNH---RVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIAR-RCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK--TL
--LKLVERLGAGQFGEVWMGYYN-GHTKVAVKSLK-QGSM-SPDAFLAEANLMKQLQHQRLVRLYAVVT-----QEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEER--------NYIHRDLRAANILVSDTLSCKIADFGLARLI----E--DNEYTAREGAKFPIKWTAPEAIN------YGTFTIKSDVWSFGILLTEIVTHGR----------IPYPGM-----TNPEVIQNLERGYRMVRPDNCP------EELYQLMRLCWKERPEDRPTFDYLRSVL--
-L-RLEVKLGQGCFGEVWMGTWN-GTTRVAIKTLK-PGTM-SPEAFLQEAQVMKKLRHEKLVQLYAVVS-----EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERM--------NYVHRDLRAANILVGENLVCKVADFGLARLI----E--DNEYTARQGAKFPIKWTAPEAAL------YGRFTIKSDVWSFGILLTELTTKGR----------VPYPGM-----VNREVLDQVERGYRMPCPPECP------ESLHDLMCQCWRKEPEERPTFEYLQAFL--
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