KIDFamMap

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Kinase profiling results of kinases in KIF 1H00A_FAP (CDK2, PDB code: 1H00, chain A)
Template Kinase: CDK2 Template inhibitor: AC1NAE4F	50 kinases in the family Kinase profiling results source 1. Davis et al. Nature Biotechnology.29, 1046-51 2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45 Similarity between template inhibitor and test compounds of profiling results Atom pair threshold: Checkmol threshold:

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM

>10uM

Kinase	Kinase group	C	C	C	C
ROCK2	AGC
PRKCQ	AGC
DAPK3	CAMK
STK17A	CAMK
STK17B	CAMK
DCLK3	CAMK
PHKG1	CAMK
PHKG2	CAMK
PIM3	CAMK
PRKD1	CAMK
CHEK2	CAMK
CDK2	CMGC
CDK4	CMGC
CDK7	CMGC
HIPK4	CMGC
GSK3B	CMGC
MAPK4	CMGC
MAPK6	CMGC
MAPK10	CMGC
MAPK9	CMGC
NLK	CMGC
AURKC	Other
GAK	Other
SBK1	Other
STK35	Other
STK36	Other
SLK	STE
MAP2K1	STE
MAP2K5	STE
ABL1	TK
AXL	TK
DDR1	TK
DDR2	TK
EPHA1	TK
EPHB1	TK
FGFR2	TK
FGFR3	TK
FGFR4	TK
MET	TK
FGR	TK
FYN	TK
SRC	TK
YES1	TK
BLK	TK
HCK	TK
LCK	TK
PTK6	TK
SRMS	TK
IRAK4	TKL
TNNI3K	TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%

100%

Kinase	Kinase group	C	C	C	C
PRKCQ	AGC
ROCK2	AGC
CHEK2	CAMK
DAPK3	CAMK
PHKG1	CAMK
PHKG2	CAMK
PIM3	CAMK
PRKD1	CAMK
STK17A	CAMK
CDK2	CMGC
CDK4	CMGC
CDK7	CMGC
GSK3B	CMGC
HIPK4	CMGC
MAPK10	CMGC
MAPK9	CMGC
NLK	CMGC
AURKC	Other
MAP2K1	STE
SLK	STE
ABL1	TK
AXL	TK
BLK	TK
DDR2	TK
EPHA1	TK
EPHB1	TK
FGFR2	TK
FGFR3	TK
FGFR4	TK
FGR	TK
FYN	TK
HCK	TK
LCK	TK
MET	TK
PTK6	TK
SRC	TK
SRMS	TK
YES1	TK
IRAK4	TKL