Kinase profiling results of kinases in KIF 2C69A_CT8 (CDK2, PDB code: 2C69, chain A)
Template Kinase: CDK2
Template inhibitor: CT8

22 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
ROCK2AGC 
CDK2CMGC 
CDK4CMGC 
CDC2L6CMGC 
CDK8CMGC 
CLK4CMGC 
DYRK1ACMGC 
GSK3BCMGC 
MAPK10CMGC 
MAPK14CMGC 
AURKBOther 
CHUKOther 
PLK1Other 
ABL1TK 
DDR1TK 
PTK2TK 
JAK2TK 
JAK3TK 
SRCTK 
LCKTK 
PTK6TK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
ROCK2AGC    
CDC2CMGC    
CDC2CMGC    
CDK2CMGC    
CDK4CMGC    
CLK4CMGC    
DYRK1ACMGC    
GSK3BCMGC    
MAPK10CMGC    
MAPK14CMGC    
AURKBOther    
CHUKOther    
PLK1Other    
ABL1TK    
JAK2TK    
JAK3TK    
LCKTK    
PTK2TK    
PTK6TK    
SRCTK